Casirivimab–Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19

DOI record: { "DOI": "10.1016/j.eclinm.2021.101102", "ISSN": [ "2589-5370" ], "URL": "http://dx.doi.org/10.1016/j.eclinm.2021.101102", "alternative-id": [ "S2589537021003825" ], "article-number": "101102", "author": [ { "ORCID": "http://orcid.org/0000-0001-5248-0227", "affiliation": [], "authenticated-orcid": false, "family": "Razonable", "given": "Raymund R.", "sequence": "first" }, { "affiliation": [], "family": "Pawlowski", "given": "Colin", "sequence": "additional" }, { "affiliation": [], "family": "O'Horo", "given": "John C.", "sequence": "additional" }, { "affiliation": [], "family": "Arndt", "given": "Lori L.", "sequence": "additional" }, { "ORCID": "http://orcid.org/0000-0003-4723-689X", "affiliation": [], "authenticated-orcid": false, "family": "Arndt", "given": "Richard", "sequence": "additional" }, { "affiliation": [], "family": "Bierle", "given": "Dennis M.", "sequence": "additional" }, { "affiliation": [], "family": "Borgen", "given": "Molly Destro", "sequence": "additional" }, { "ORCID": "http://orcid.org/0000-0003-2517-638X", "affiliation": [], "authenticated-orcid": false, "family": "Hanson", "given": "Sara N.", "sequence": "additional" }, { "affiliation": [], "family": "Hedin", "given": "Michelle C.", "sequence": "additional" }, { "affiliation": [], "family": "Lenehan", "given": "Patrick", "sequence": "additional" }, { "affiliation": [], "family": "Puranik", "given": "Arjun", "sequence": "additional" }, { "affiliation": [], "family": "Seville", "given": "Maria T", "sequence": "additional" }, { "affiliation": [], "family": "Speicher", "given": "Leigh L.", "sequence": "additional" }, { "affiliation": [], "family": "Tulledge-Scheitel", "given": "Sidna M.", "sequence": "additional" }, { "affiliation": [], "family": "Venkatakrishnan", "given": "AJ", "sequence": "additional" }, { "affiliation": [], "family": "Wilker", "given": "Caroline G.", "sequence": "additional" }, { "affiliation": [], "family": "Badley", "given": "Andrew D.", "sequence": "additional" }, { "affiliation": [], "family": "Ganesh", "given": "Ravindra", "sequence": "additional" } ], "container-title": "EClinicalMedicine", "container-title-short": "EClinicalMedicine", "content-domain": { "crossmark-restriction": false, "domain": [] }, "created": { "date-parts": [ [ 2021, 8, 30 ] ], "date-time": "2021-08-30T11:00:58Z", "timestamp": 1630321258000 }, "deposited": { "date-parts": [ [ 2021, 10, 25 ] ], "date-time": "2021-10-25T21:24:45Z", "timestamp": 1635197085000 }, "funder": [ { "DOI": "10.13039/100007048", "doi-asserted-by": "publisher", "name": "Mayo Clinic" }, { "DOI": "10.13039/100004337", "doi-asserted-by": "publisher", "name": "Roche" }, { "DOI": "10.13039/100005564", "doi-asserted-by": "publisher", "name": "Gilead Sciences" } ], "indexed": { "date-parts": [ [ 2023, 5, 20 ] ], "date-time": "2023-05-20T05:19:10Z", "timestamp": 1684559950727 }, "is-referenced-by-count": 93, "issued": { "date-parts": [ [ 2021, 10 ] ] }, "language": "en", "license": [ { "URL": "https://www.elsevier.com/tdm/userlicense/1.0/", "content-version": "tdm", "delay-in-days": 0, "start": { "date-parts": [ [ 2021, 10, 1 ] ], "date-time": "2021-10-01T00:00:00Z", "timestamp": 1633046400000 } }, { "URL": "http://creativecommons.org/licenses/by-nc-nd/4.0/", "content-version": "vor", "delay-in-days": 0, "start": { "date-parts": [ [ 2021, 8, 12 ] ], "date-time": "2021-08-12T00:00:00Z", "timestamp": 1628726400000 } } ], "link": [ { "URL": "https://api.elsevier.com/content/article/PII:S2589537021003825?httpAccept=text/xml", "content-type": "text/xml", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://api.elsevier.com/content/article/PII:S2589537021003825?httpAccept=text/plain", "content-type": "text/plain", "content-version": "vor", "intended-application": "text-mining" } ], "member": "78", "original-title": [], "page": "101102", "prefix": "10.1016", "published": { "date-parts": [ [ 2021, 10 ] ] }, "published-print": { "date-parts": [ [ 2021, 10 ] ] }, "publisher": "Elsevier BV", "reference": [ { "article-title": "An EUA for bamlanivimab-a monoclonal antibody for COVID-19", "journal-title": "JAMA", "key": "10.1016/j.eclinm.2021.101102_bib0001", "year": "2020" }, { "article-title": "An EUA for casirivimab and imdevimab for COVID-19", "first-page": "201", "issue": "1614", "journal-title": "Med Lett Drugs Ther", "key": "10.1016/j.eclinm.2021.101102_bib0002", "volume": "62", "year": "2020" }, { "article-title": "An EUA for bamlanivimab and etesevimab for COVID-19", "first-page": "49", "issue": "1621", "journal-title": "Med Lett Drugs Ther", "key": "10.1016/j.eclinm.2021.101102_bib0003", "volume": "63", "year": "2021" }, { "DOI": "10.1038/s41401-020-0485-4", "article-title": "Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19", "author": "Huang", "doi-asserted-by": "crossref", "first-page": "1141", "issue": "9", "journal-title": "Acta Pharmacol Sin", "key": "10.1016/j.eclinm.2021.101102_bib0004", "volume": "41", "year": "2020" }, { "DOI": "10.1056/NEJMoa2035002", "article-title": "REGN-COV2, a neutralizing antibody cocktail, in outpatients with Covid-19", "author": "Weinreich", "doi-asserted-by": "crossref", "first-page": "238", "issue": "3", "journal-title": "N Engl J Med", "key": "10.1016/j.eclinm.2021.101102_bib0005", "volume": "384", "year": "2021" }, { "key": "10.1016/j.eclinm.2021.101102_bib0006", "unstructured": "Bhimraj A, Morgan R, Schumaker AH, et al. Infectious diseases society of America guidelines on the treatment and management of patients with COVID-19. Available at: https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/. Accessed 05/10/ 2021." }, { "key": "10.1016/j.eclinm.2021.101102_bib0007", "unstructured": "NIH. Anti-SARS-CoV-2 monoclonal antibodies. Available at: https://www.covid19treatmentguidelines.nih.gov/anti-sars-cov-2-antibody-products/anti-sars-cov-2-monoclonal-antibodies/. Accessed May 10, 2021." }, { "author": "Razonable", "key": "10.1016/j.eclinm.2021.101102_bib0008", "series-title": "A framework for outpatient infusion of anti-spike monoclonal antibodies to high-risk patients with mild to moderate coronavirus disease-19: the mayo clinic model", "year": "2021" }, { "DOI": "10.1111/j.1467-6419.2007.00527.x", "article-title": "Some practical guidance for the implementation of propensity score matching", "author": "Caliendo", "doi-asserted-by": "crossref", "first-page": "31", "issue": "1", "journal-title": "J Econ Surv", "key": "10.1016/j.eclinm.2021.101102_bib0009", "volume": "22", "year": "2008" }, { "DOI": "10.1093/ije/dyy120", "article-title": "Evaluating large-scale propensity score performance through real-world and synthetic data experiments", "author": "Tian", "doi-asserted-by": "crossref", "first-page": "2005", "issue": "6", "journal-title": "Int J Epidemiol", "key": "10.1016/j.eclinm.2021.101102_bib0010", "volume": "47", "year": "2018" }, { "author": "Hosmer", "key": "10.1016/j.eclinm.2021.101102_bib0011", "series-title": "Applied survival analysis: regression modeling of time-to-event data", "year": "2008" }, { "key": "10.1016/j.eclinm.2021.101102_bib0012", "unstructured": "Davidson-Pilon C, Kalderstam J, Zivich P, et al. CamDavidsonPilon/lifelines: v0. 21.3. Zenodo 2019." }, { "DOI": "10.1001/jama.2020.6775", "article-title": "Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area", "author": "Richardson", "doi-asserted-by": "crossref", "first-page": "2052", "issue": "20", "journal-title": "JAMA", "key": "10.1016/j.eclinm.2021.101102_bib0013", "volume": "323", "year": "2020" }, { "DOI": "10.1016/S0140-6736(20)30566-3", "article-title": "Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study", "author": "Zhou", "doi-asserted-by": "crossref", "first-page": "1054", "issue": "10229", "journal-title": "Lancet", "key": "10.1016/j.eclinm.2021.101102_bib0014", "volume": "395", "year": "2020" }, { "DOI": "10.1056/NEJMoa2029849", "article-title": "SARS-CoV-2 neutralizing antibody LY-CoV555 in outpatients with Covid-19", "author": "Chen", "doi-asserted-by": "crossref", "first-page": "229", "issue": "3", "journal-title": "N Engl J Med", "key": "10.1016/j.eclinm.2021.101102_bib0015", "volume": "384", "year": "2021" }, { "article-title": "Telemedicine consultations and follow-up of patients with COVID-19", "author": "Crane", "issue": "9s", "journal-title": "Mayo Clin Proc", "key": "10.1016/j.eclinm.2021.101102_bib0016", "volume": "95", "year": "2020" }, { "article-title": "Managing patients in the COVID-19 pandemic: a virtual multidisciplinary approach", "author": "Ganesh", "first-page": "118", "issue": "1", "journal-title": "Mayo Clinic Proc: Innovat, Qual Outcomes", "key": "10.1016/j.eclinm.2021.101102_bib0017", "volume": "5", "year": "2021" }, { "author": "O'Horo", "key": "10.1016/j.eclinm.2021.101102_bib0018", "series-title": "Outcomes of COVID-19 with the mayo clinic model of care and research", "year": "2020" }, { "DOI": "10.1056/NEJMoa2007764", "article-title": "Remdesivir for the treatment of Covid-19 - final report", "author": "Beigel", "doi-asserted-by": "crossref", "first-page": "1813", "issue": "19", "journal-title": "N Engl J Med", "key": "10.1016/j.eclinm.2021.101102_bib0019", "volume": "383", "year": "2020" }, { "article-title": "Dexamethasone in hospitalized patients with Covid-19 - preliminary report", "author": "Group", "first-page": "693", "issue": "8", "journal-title": "N Engl J Med", "key": "10.1016/j.eclinm.2021.101102_bib0020", "volume": "384", "year": "2020" }, { "article-title": "Trends in mortality of hospitalised COVID-19 patients: a single centre observational cohort study from Spain", "author": "Garcia-Vidal", "journal-title": "Lancet Reg Health Eur", "key": "10.1016/j.eclinm.2021.101102_bib0021", "volume": "3", "year": "2021" }, { "DOI": "10.12788/jhm.3552", "article-title": "Trends in COVID-19 risk-adjusted mortality rates", "author": "Horwitz", "doi-asserted-by": "crossref", "first-page": "90", "issue": "2", "journal-title": "J Hosp Med", "key": "10.1016/j.eclinm.2021.101102_bib0022", "volume": "16", "year": "2021" }, { "key": "10.1016/j.eclinm.2021.101102_bib0023", "unstructured": "Medicine JHU. Coronavirus resource center. Available at: https://coronavirus.jhu.edu/. Accessed 06/02/ 2021." } ], "reference-count": 23, "references-count": 23, "relation": {}, "resource": { "primary": { "URL": "https://linkinghub.elsevier.com/retrieve/pii/S2589537021003825" } }, "score": 1, "short-title": [], "source": "Crossref", "subject": [ "General Medicine" ], "subtitle": [], "title": "Casirivimab–Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19", "type": "journal-article", "volume": "40" }