Abstract: Case Characteristics, Clinical Data, And Outcomes of Hospitalized COVID-19 Patients In Qom Province, Iran: A Prospective Cohort Study Mohamad Amin Pourhoseingholi Shahid Beheshti University of Medical Sciences Hosein Yousefi Qom University of Medical Science and Health Services Hassan Fatemi Manesh Qom University of Medical Science and Health Services Nima Najafian Motahaver Qom University of Medical Science and Health Services Zahra Heydari Qom University of Medical Science and Health Services Mehdi Azizmohammad Looha Shahid Beheshti University of Medical Sciences Nazanin Taraghikhah Shahid Beheshti University of Medical Sciences Maryam Yazdi Qom University of Medical Science and Health Services Zahra Salami Qom University of Medical Science and Health Services Elmira Moallemi Qom University of Medical Science and Health Services Seyed Hasan Adeli (  adeli@muq.ac.ir ) Qom University of Medical Science and Health Services Research Article Keywords: COVID-19, Pandemic, Iran, Risk factor, Cohort Posted Date: May 26th, 2021 DOI: https://doi.org/10.21203/rs.3.rs-365321/v2 License:   This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/25 Abstract The outbreak of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) dates back to December 2019 in China. Iran has been one of the most virus inflicted countries. The aim of this study was to report demographics, signs and symptoms, laboratory findings, therapeutic approaches, and outcomes. This observational cohort study was performed from 20th February 2020 to 20th July 2020. Patients’ information was recorded in their medical files. Multivariable analysis was performed to assess demographics, signs and symptoms, paraclinical data, treatments, outcomes of disease, and finding the risk factors of death subject to COVID-19. Of all 2468 participants, the mean age was 57.9±17.6 years and 56.8% of patients were male. The most significant comorbidities were seen among those who have Hypertension and Diabetes Mellitus. 14.42% were admitted to ICU, and 17.2% died in hospital. The significant risk factors of death were ageing, male gender, HTN, CHF, CVA, CKD, increasing ESR, PT, WBC, liver function tests, and decreasing Oxygen saturation. Incontinent results in the case of COVID-19 outcomes and deathrelated risk factors attribute to marked differences in demographics and health care systems. The patients with hazardous risk factors must be detected urgently and monitored closely to save more lives.