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All Studies   Meta Analysis       

Adjuvant Therapeutic Effects of Melatonin Agonist on Hospitalized Patients With Confirmed or Suspected COVID-19

Piovezan et al., NCT04470297, MELCOV2020, NCT04470297
Mar 2021  
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Melatonin for COVID-19
11th treatment shown to reduce risk in December 2020, now with p = 0.0000002 from 18 studies.
Lower risk for mortality, ventilation, and recovery.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 110 treatments. c19early.org
Estimated 100 patient melatonin late treatment RCT with results not reported over 3 years after estimated completion.
3 melatonin RCTs have results missing long after expected1-3
The trials report a total of 268 patients, with 2 trials having actual enrollment of 168, and the other estimated.
Piovezan et al., 1 Mar 2021, Double Blind Randomized Controlled Trial, placebo-controlled, Brazil, trial NCT04470297 (history) (MELCOV2020). Contact: rdpiovezan@gmail.com.
This PaperMelatoninAll
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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