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0 0.5 1 1.5 2+ Mortality 35% Improvement Relative Risk c19early.org/o Pinzón et al. Colchicine for COVID-19 LATE TREATMENT Favors colchicine Favors control
Clinical Outcome of Patients with COVID-19 Pneumonia Treated with Corticosteroids and Colchicine in Colombia
Pinzón et al., Research Square, doi:10.21203/rs.3.rs-94922/v1 (Preprint)
23 Oct 2020    Source   PDF   Share   Tweet
Retrospective 301 pneumonia patients in Colombia showing lower mortality with colchicine treatment.
Although the 35% lower mortality is not statistically significant, it is consistent with the significant 37% lower mortality [24‑47%] from meta analysis of the 33 mortality results to date.
risk of death, 34.5% lower, RR 0.65, p = 0.18, treatment 14 of 145 (9.7%), control 23 of 156 (14.7%), NNT 20, odds ratio converted to relative risk.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Pinzón et al., 23 Oct 2020, retrospective, Colombia, preprint, 9 authors, dosage 1mg days 1-14.
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This PaperColchicineAll
Late treatment
is less effective
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