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0 0.5 1 1.5 2+ Death/mechanical ventil.. 55% Improvement Relative Risk c19early.org/z Jiménez et al. Zinc for COVID-19 Sufficiency Are zinc levels associated with COVID-19 outcomes? Prospective study of 100 patients in Spain (September 2020 - April 2021) Lower progression with higher zinc levels (not stat. sig., p=0.22) Jiménez et al., J. Trace Elements in Medicine an.., doi:10.1016/j.jtemb.2023.127200 Favors zinc Favors control

Zinc Levels of Patients With A Moderate to Severe COVID-19 Infection at Hospital Admission and After 4th Days of Ward Hospitalization and Their Clinical Outcome

Jiménez et al., Journal of Trace Elements in Medicine and Biology, doi:10.1016/j.jtemb.2023.127200
Jiménez et al., Zinc Levels of Patients With A Moderate to Severe COVID-19 Infection at Hospital Admission and After 4th Days.., Journal of Trace Elements in Medicine and Biology, doi:10.1016/j.jtemb.2023.127200
May 2023   Source   PDF  
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Prospective analysis of 100 hospitalized COVID-19 patients in Spain, showing higher risk of death/mechanical ventilation/ICU admission with zinc levels <79µg/dL, without statistical significance.
risk of death/mechanical ventilation/ICU admission, 54.6% lower, OR 0.45, p = 0.21, high zinc levels (≥79µg/dL) 30, low zinc levels (<79µg/dL) 70, adjusted per study, inverted to make OR<1 favor high zinc levels (≥79µg/dL), RR approximated with OR.
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Jiménez et al., 13 May 2023, prospective, Spain, peer-reviewed, 8 authors, study period 4 September, 2020 - 24 April, 2021.
Contact: arturocorbaton@yahoo.es.
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Abstract: Journal Pre-proof Zinc Levels of Patients With A Moderate to Severe COVID-19 Infection at Hospital Admission and After 4th Days of Ward Hospitalization and Their Clinical Outcome Laura Rodelgo Jiménez, Arturo Corbatón Anchuelo, Pablo Matías Soler, Raúl Perales Muñoz, Manuel Fuentes Ferrer, Iñigo Sagastagoitia Fornie, Marina Gil Mosquera, Mercedes MartínezNovillo González PII: S0946-672X(23)00076-7 DOI: https://doi.org/10.1016/j.jtemb.2023.127200 Reference: JTEMB127200 To appear in: Journal of Trace Elements in Medicine and Biology Received date: 30 November 2022 Revised date: 8 April 2023 Accepted date: 12 May 2023 Please cite this article as: Laura Rodelgo Jiménez, Arturo Corbatón Anchuelo, Pablo Matías Soler, Raúl Perales Muñoz, Manuel Fuentes Ferrer, Iñigo Sagastagoitia Fornie, Marina Gil Mosquera and Mercedes Martínez-Novillo González, Zinc Levels of Patients With A Moderate to Severe COVID-19 Infection at Hospital Admission and After 4th Days of Ward Hospitalization and Their Clinical Outcome, Journal of Trace Elements in Medicine and Biology, (2023) doi:https://doi.org/10.1016/j.jtemb.2023.127200 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2023 Published by Elsevier. Zinc levels of patients with a moderate to severe COVID-19 infection at hospital admission and after 4th days of ward hospitalization and their clinical outcome. Authors: Laura Rodelgo Jiméneza, Arturo Corbatón Anchuelob,c,d, Pablo Matías Solerd, Raúl Perales Muñozd, Manuel Fuentes Ferrere, Iñigo Sagastagoitia Fornief, Marina Gil Mosquerad, Mercedes Martínez-Novillo Gonzáleza. re -p ro of (a) Instituto de Medicina de Laboratorio (IML), Instituto de Investigación del Hospital Clínico San Carlos (IdISSC)del Hospital Clínico San Carlos, Madrid, Spain. (b) Grupo de Riesgo Vascular, Instituto de Investigación del Hospital Clínico San Carlos (IdISSC), Madrid, Spain. (c) Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Madrid, Spain. (d) Grupo de Patología de Urgencias y Emergencias, Instituto de Investigación del Hospital Clínico San Carlos (IdISSC), Madrid, Spain. (e) Unidad de Investigación in the Hospital Universitario Nuestra Señora de Candelaria in Santa Cruz de Tenerife (Spain). (f) Grupo de Infecciosas/VIH, Instituto de Investigación del Hospital Clínico San Carlos (IdISSC), Madrid Spain. lP Corresponding author: Arturo Corbatón-Anchuelo. E-mail adress: arturocorbaton@yahoo.es Jo u rn a Address correspondence: ABSTRACT Background. Previous studies associate the disturbance of the Zinc (Zn) status with the severity of the disease and the inflammatory process in the critically ill patient. This decrease in Zn concentrations is an indicator of poor prognosis. Our aim was to evaluate Zn levels at admission and after four days, and to study if lower Zn levels at those days were related to a worse clinical outcome. Material and methods. Observational cohort study at a tertiary..
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