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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Death/mechanical ventil.. 55% Improvement Relative Risk Zinc for COVID-19  Jiménez et al.  Sufficiency Are zinc levels associated with COVID-19 outcomes? Prospective study of 100 patients in Spain (September 2020 - April 2021) Lower progression with higher zinc levels (not stat. sig., p=0.22) c19early.org Jiménez et al., J. Trace Elements in M.., May 2023 Favors zinc Favors control

Zinc Levels of Patients With A Moderate to Severe COVID-19 Infection at Hospital Admission and After 4th Days of Ward Hospitalization and Their Clinical Outcome

Jiménez et al., Journal of Trace Elements in Medicine and Biology, doi:10.1016/j.jtemb.2023.127200
May 2023  
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Zinc for COVID-19
2nd treatment shown to reduce risk in July 2020
 
*, now known with p = 0.0000013 from 44 studies, recognized in 11 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments. c19early.org
Prospective analysis of 100 hospitalized COVID-19 patients in Spain, showing higher risk of death/mechanical ventilation/ICU admission with zinc levels <79µg/dL, without statistical significance.
risk of death/mechanical ventilation/ICU admission, 54.6% lower, OR 0.45, p = 0.21, high zinc levels (≥79µg/dL) 30, low zinc levels (<79µg/dL) 70, adjusted per study, inverted to make OR<1 favor high zinc levels (≥79µg/dL), RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Jiménez et al., 13 May 2023, prospective, Spain, peer-reviewed, 8 authors, study period 4 September, 2020 - 24 April, 2021. Contact: arturocorbaton@yahoo.es.
This PaperZincAll
Zinc levels of patients with a moderate to severe COVID-19 infection at hospital admission and after 4th days of ward hospitalization and their clinical outcome
Laura Rodelgo Jiménez, Arturo Corbatón Anchuelo, Pablo Matías Soler, Raúl Perales Muñoz, Manuel Fuentes Ferrer, Iñigo Sagastagoitia Fornie, Marina Gil Mosquera, Mercedes Martínez-Novillo González
Journal of Trace Elements in Medicine and Biology, doi:10.1016/j.jtemb.2023.127200
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Authors' Contributions LRJ and ACA are responsible for conceiving and designing the study as well as data interpretation and preparation of the draft of the manuscript. ACA, LRJ, PMS, RPM and MGM participated actively in the development of the field study. MFF extracted the data and take responsibility together with LRJ and ACA for the integrity of the analyses. MMG and ISF participated in the design and development of the field studies. MMG participated in the critical revision and gave final approval of the manuscript to be published. Declaration of Competing Interest The authors declare no conflict of interest. Authorship contributions
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