Low blood zinc concentrations in patients with poor clinical outcome during SARS-CoV-2 infection: is there a need to supplement with zinc COVID-19 patients?
Grégory Dubourg, Jean-Christophe Lagier, Philippe Brouqui, Jean-Paul Casalta, Véronique Jacomo, Bernard La Scola, Jean-Marc Rolain, Didier Raoult
Journal of Microbiology, Immunology and Infection, doi:10.1016/j.jmii.2021.01.012
Among 275 patients with COVID-19, we found that median blood zinc level was significantly lower in patients with poor clinical outcome (N Z 75) as compared to patients with good clinical outcome (N Z 200) (840 mg/L versus 970 mg/L; p < 0.0001), suggesting that zinc supplementation could be useful for patients with severe COVID-19.
Declaration of competing interest None to declare.
Appendix A. Supplementary data Supplementary data to this article can be found online at https://doi.org/10.1016/j.jmii.2021.01.012.
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