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0 0.5 1 1.5 2+ Case 16% per SD change Improvement Relative Risk c19early.org/b9 Deschasaux-Tanguy et al. Vitamin B9 Prophylaxis Does vitamin B9 reduce COVID-19 infections? Retrospective 7,766 patients in France Fewer cases with vitamin B9 (p=0.02) Deschasaux-Tanguy et al., BMC Medicine, doi:10.1186/s12916-021-02168-1 Favors vitamin B9 Favors control

Nutritional risk factors for SARS-CoV-2 infection: a prospective study within the NutriNet-Santé cohort

Deschasaux-Tanguy et al., BMC Medicine, doi:10.1186/s12916-021-02168-1
Deschasaux-Tanguy et al., Nutritional risk factors for SARS-CoV-2 infection: a prospective study within the NutriNet-Santé cohort, BMC Medicine, doi:10.1186/s12916-021-02168-1
Nov 2021   Source   PDF  
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Analysis of 7,766 adults in France, showing higher intakes of vitamin C, folate, vitamin K, dietary fibre, and fruit and vegetables associated with lower seropositivity.
This study includes vitamin B9, vitamin C, and diet.
risk of case, 16.0% lower, OR 0.84, p = 0.02, RR approximated with OR, per standard deviation change.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Deschasaux-Tanguy et al., 30 Nov 2021, retrospective, France, peer-reviewed, 95 authors.
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Nutritional risk factors for SARS-CoV-2 infection: prospective study from the NutriNet-Sante ´cohort
Mathilde Touvier, M Deschasaux-Tanguy, L Bourhis, N Druesne-Pecollo, Y Esseddik, P Galan, S Hercberg, X De Lamballerie, F Carrat
17.3% in men; 35.8% and 18.4% in women) and 10.3% to injuries (4.9% among people aged 65 or more at time of death; 34.5% among people aged 25-44). Approximately 27% of the deaths registered were IDDs, representing approximately 1.8 million YLLs. Conclusions: These preliminary results confirm the importance of YLLs as a metric to target preventive strategies according to age. Moreover, by quantifying IDDs, we highlight that data gaps are important even in settings with highly developed health information systems. Next steps include applying an IDD redistribution methodology, aspirational life table and computing subnational YLLs. The French collaborative initiative should address those gaps and propose national and subnational burden metrics in the following months. Key messages: Methodological and data requirements to compute YLLs constitute a challenge even in settings with developed health information systems, highlighting the need of national institutional collaborations. Highlight data gaps in terms of ill-defined deaths in mortality database.
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