Statistically significant lower risk is seen for ventilation, hospitalization, recovery, cases, and viral clearance. 11 studies from 10 independent teams in 8 countries show statistically significant improvements.
Meta analysis using the most serious outcome reported shows 43% [24‑57%] lower risk. Results are similar for Randomized Controlled Trials and higher quality studies. Early treatment is more effective than late treatment.
Results are robust — in exclusion sensitivity analysis 11 of 14 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments may be more effective. The quality of non-prescription supplements can vary widely Crawford, Crighton.
All data to reproduce this paper and sources are in the appendix. Other meta analyses show significant improvements with nigella sativa for mortality Kow, Umer and viral clearance Umer.
2 meta analyses show significant improvements with nigella sativa for mortality
Kow,
Umer and
viral clearance
Umer.
Covid Analysis et al., Apr 2024, preprint, 1 author.