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All Studies   Meta Analysis    Recent:   

Electrolytes, Zinc and Vitamin D3 in COVID-19 Patients with Cardiovascular Complications

AlKhuzaie et al., Problems of Virology, doi:10.36233/0507-4088-236
Jul 2024  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now with p < 0.00000000001 from 122 studies, recognized in 9 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,400+ studies for 81 treatments. c19early.org
Retrospective 142 COVID-19 patients and 50 controls showing significantly lower levels of zinc, vitamin D, calcium, potassium, and sodium in COVID-19 patients compared to controls. Lower levels of zinc, vitamin D, calcium, and sodium were associated with disease severity.
Study covers vitamin D and zinc.
AlKhuzaie et al., 5 Jul 2024, retrospective, Iraq, peer-reviewed, 3 authors.
This PaperVitamin DAll
Electrolytes, Zinc and Vitamin D3 in COVID-19 Patients with Cardiovascular Complications
Ali Abdel-Moneim Mohammed-Hussain Alkhuzaie, Enas Abdul Kareem Jabbar, Bushra Jabbar Albadry
Problems of Virology, doi:10.36233/0507-4088-236
Introduction. COVID-19 is strongly linked to cardiovascular disease, with direct myocardial injury and systemic inflammation as common mechanisms. Pre-existing or infection-induced cardiovascular disease worsens the outcomes for COVID-19 patients. Materials and methods. To estimate the serum electrolytes (Na + , K + , Ca ++ , Zn) and vitamin D 3 , the study depended on ichroma ii device for Vitamin D 3 and Chemistry Analyzer for electrolytes in patient samples. Results. A study was conducted on 192 individuals diagnosed with COVID-19, including 35 critical cases, 53 severe cases, 54 moderate cases, and 50 individuals in a control group. The age group with the highest prevalence of infection was between 50-69 years, while the lowest prevalence was observed in those under 30 years. The study found significant decreases in calcium, potassium, sodium, zinc, and vitamin D 3 levels among COVID-19 patients compared to the control group. Zinc and vitamin D 3 levels showed a significant correlation with sex, with males experiencing a decline in zinc levels and females having lower vitamin D 3 levels. The concentration of calcium, sodium, and zinc showed a negative correlation with age, with older patients having the lowest levels. COVID-19 patients with chronic cardiac issues and high blood pressure exhibited the lowest levels of these markers. The severity of the disease also had a detrimental impact on electrolyte levels, zinc, and vitamin D 3 , with critical cases showing the lowest levels. The complications such as heart failure were associated with lower levels of potassium, sodium, and zinc. Conclusion. In conclusion, the study revealed significant associations between COVID-19 and decreased electrolyte levels, zinc, and vitamin D 3 . Sex and age were found to be correlated with these markers. Patients with chronic cardiac issues and high blood pressure exhibited the lowest levels of these markers. The severity of the disease was also linked to lower electrolyte levels, zinc, and vitamin D 3 . Complications such as heart failure were associated with decreased levels of potassium, sodium, and zinc.
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To estimate the serum electrolytes (Na+, K+, Ca++, Zn) and vitamin D3, ' 'the study depended on ichroma ii device for Vitamin D3 and Chemistry Analyzer for ' 'electrolytes in patient samples.\r\n' 'Results. A study was conducted on 192 individuals diagnosed with COVID-19, including 35 ' 'critical cases, 53 severe cases, 54 moderate cases, and 50 individuals in a control group. ' 'The age group with the highest prevalence of infection was between 50‒69 years, while the ' 'lowest prevalence was observed in those under 30 years. The study found significant decreases ' 'in calcium, potassium, sodium, zinc, and vitamin D3 levels among COVID-19 patients compared ' 'to the control group. Zinc and vitamin D3 levels showed a significant correlation with sex, ' 'with males experiencing a decline in zinc levels and females having lower vitamin D3 levels. ' 'The concentration of calcium, sodium, and zinc showed a negative correlation with age, with ' 'older patients having the lowest levels. 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