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0 0.5 1 1.5 2+ Severe/critical COVID-19 93% Improvement Relative Risk c19early.org/d Ye et al. Vitamin D for COVID-19 Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 62 patients in China Lower hospitalization with higher vitamin D levels (p=0.034) Ye et al., J. the American College of Nutrition, doi:10.1080/07315724.2020.182600 Favors vitamin D Favors control
Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity? A Case-Control Study
Ye et al., Journal of the American College of Nutrition, doi:10.1080/07315724.2020.182600
Ye et al., Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity? A Case-Control Study, Journal of the American College of Nutrition, doi:10.1080/07315724.2020.182600
Oct 2020   Source   PDF  
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Case control study in China comparing 62 patients with 80 healthy controls showing vitamin D deficiency is a risk factor for COVID-19, especially for severe/critical cases.
risk of severe/critical COVID-19, 93.4% lower, RR 0.07, p = 0.03, high D levels 2 of 36 (5.6%), low D levels 8 of 26 (30.8%), NNT 4.0, adjusted per study, inverted to make RR<1 favor high D levels, >50nmol/L.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Ye et al., 13 Oct 2020, retrospective, China, peer-reviewed, 18 authors.
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Abstract: Journal of the American College of Nutrition ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/uacn20 Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study Kun Ye, Fen Tang, Xin Liao, Benjamin A. Shaw, Meiqiu Deng, Guangyi Huang, Zhiqiang Qin, Xiaomei Peng, Hewei Xiao, Chunxia Chen, Xiaochun Liu, Leping Ning, Bangqin Wang, Ningning Tang, Min Li, Fan Xu, Shao Lin & Jianrong Yang To cite this article: Kun Ye, Fen Tang, Xin Liao, Benjamin A. Shaw, Meiqiu Deng, Guangyi Huang, Zhiqiang Qin, Xiaomei Peng, Hewei Xiao, Chunxia Chen, Xiaochun Liu, Leping Ning, Bangqin Wang, Ningning Tang, Min Li, Fan Xu, Shao Lin & Jianrong Yang (2021) Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study, Journal of the American College of Nutrition, 40:8, 724-731, DOI: 10.1080/07315724.2020.1826005 To link to this article: https://doi.org/10.1080/07315724.2020.1826005 Published online: 13 Oct 2020. Submit your article to this journal Article views: 8281 View related articles View Crossmark data Citing articles: 41 View citing articles Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=uacn20 JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION 2021, VOL. 40, NO. 8, 724–731 https://doi.org/10.1080/07315724.2020.1826005 Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study Kun Yea, Fen Tangb, Xin Liaoc, Benjamin A. Shawd, Meiqiu Denga, Guangyi Huangb, Zhiqiang Qine, Xiaomei Penga, Hewei Xiaoc, Chunxia Chenf, Xiaochun Liug, Leping Ningg, Bangqin Wangh , Ningning Tangb, Min Lib, Fan Xub, Shao Lini and Jianrong Yangj a Department of Nephrology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; bDepartment of Ophthalmology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; cDepartment of Scientific Research, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; dDepartment of Health Policy, Management, and Behavior, School of Public Health, University at Albany, Rensselaer, New York, USA; eDepartment of Pneumology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; fDepartment of High-pressure Oxygen, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; gDepartment of Clinical Laboratory, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; h Department of Medical Affairs, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; iDepartment of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, New York, USA; j Department of Hepatobiliary Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China ABSTRACT ARTICLE HISTORY Background: As effective medication to treat COVID-19 is currently unavailable, preventive remedies may be particularly important. Objective: To examine the relationship between serum 25-hydroxy vitamin D (25(OH)D) level and COVID-19 infection, its severity, and its clinical case characteristics. Methods: This case-control study compared serum 25(OH)D levels and rates of vitamin D deficiency (VDD) between 80 healthy controls and 62 patients diagnosed with COVID-19 and admitted to Guangxi People’s Hospital, China, 2/16/2020–3/16/2020. Cases were categorized into asymptomatic, mild/moderate,..
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