Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity? A Case-Control Study
Ye et al.,
Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity? A Case-Control Study,
Journal of the American College of Nutrition, doi:10.1080/07315724.2020.182600
Case control study in China comparing 62 patients with 80 healthy controls showing vitamin D deficiency is a risk factor for COVID-19, especially for severe/critical cases.
risk of severe/critical COVID-19, 93.4% lower, RR 0.07, p = 0.03, high D levels 2 of 36 (5.6%), low D levels 8 of 26 (30.8%), NNT 4.0, adjusted per study, inverted to make RR<1 favor high D levels, >50nmol/L.
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Ye et al., 13 Oct 2020, retrospective, China, peer-reviewed, 18 authors.
Abstract: Journal of the American College of Nutrition
ISSN: (Print) (Online) Journal homepage: https://www.tandfonline.com/loi/uacn20
Does Serum Vitamin D Level Affect COVID-19
Infection and Its Severity?-A Case-Control Study
Kun Ye, Fen Tang, Xin Liao, Benjamin A. Shaw, Meiqiu Deng, Guangyi Huang,
Zhiqiang Qin, Xiaomei Peng, Hewei Xiao, Chunxia Chen, Xiaochun Liu, Leping
Ning, Bangqin Wang, Ningning Tang, Min Li, Fan Xu, Shao Lin & Jianrong
Yang
To cite this article: Kun Ye, Fen Tang, Xin Liao, Benjamin A. Shaw, Meiqiu Deng, Guangyi Huang,
Zhiqiang Qin, Xiaomei Peng, Hewei Xiao, Chunxia Chen, Xiaochun Liu, Leping Ning, Bangqin
Wang, Ningning Tang, Min Li, Fan Xu, Shao Lin & Jianrong Yang (2021) Does Serum Vitamin D
Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study, Journal of the American
College of Nutrition, 40:8, 724-731, DOI: 10.1080/07315724.2020.1826005
To link to this article: https://doi.org/10.1080/07315724.2020.1826005
Published online: 13 Oct 2020.
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JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
2021, VOL. 40, NO. 8, 724–731
https://doi.org/10.1080/07315724.2020.1826005
Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A
Case-Control Study
Kun Yea, Fen Tangb, Xin Liaoc, Benjamin A. Shawd, Meiqiu Denga, Guangyi Huangb, Zhiqiang Qine, Xiaomei
Penga, Hewei Xiaoc, Chunxia Chenf, Xiaochun Liug, Leping Ningg, Bangqin Wangh , Ningning Tangb, Min Lib,
Fan Xub, Shao Lini and Jianrong Yangj
a
Department of Nephrology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; bDepartment of
Ophthalmology, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; cDepartment of Scientific Research, The
People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; dDepartment of Health Policy, Management, and Behavior,
School of Public Health, University at Albany, Rensselaer, New York, USA; eDepartment of Pneumology, The People’s Hospital of Guangxi
Zhuang Autonomous Region, Nanning, China; fDepartment of High-pressure Oxygen, The People’s Hospital of Guangxi Zhuang Autonomous
Region, Nanning, China; gDepartment of Clinical Laboratory, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China;
h
Department of Medical Affairs, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China; iDepartment of
Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, New York, USA;
j
Department of Hepatobiliary Surgery, The People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
ABSTRACT
ARTICLE HISTORY
Background: As effective medication to treat COVID-19 is currently unavailable, preventive remedies may be particularly important.
Objective: To examine the relationship between serum 25-hydroxy vitamin D (25(OH)D) level and
COVID-19 infection, its severity, and its clinical case characteristics.
Methods: This case-control study compared serum 25(OH)D levels and rates of vitamin D deficiency (VDD) between 80 healthy controls and 62 patients diagnosed with COVID-19 and admitted
to Guangxi People’s Hospital, China, 2/16/2020–3/16/2020. Cases were categorized into asymptomatic, mild/moderate,..
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