Outcomes in COVID-19 xylitol studies

All studies   Viral clearance   Peer-reviewed   All outcomes  
0 0.5 1 1.5+ All studies 32% 1 108 Improvement, Studies, Patients Relative Risk Viral clearance 32% 1 108 Late 32% 1 108 Xylitol for COVID-19 c19early.org July 2025 Favorsxylitol Favorscontrol
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ RENAISSANCE Cegolon 32% 0.68 [0.46-1.01] viral+ 21/50 36/58 Improvement, RR [CI] Treatment Control Tau​2​ = 0.00, I​2​ = 0.0%, p = 0.045 Late treatment 32% 0.68 [0.46-1.01] 21/50 36/58 32% lower risk All studies 32% 0.68 [0.46-1.01] 21/50 36/58 32% lower risk 1 xylitol COVID-19 study c19early.org July 2025 Tau​2​ = 0.00, I​2​ = 0.0%, p = 0.045 Effect extraction pre-specified(most serious outcome) Favors xylitol Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ RENAISSANCE Cegolon 32% 0.68 [0.46-1.01] viral+ 21/50 36/58 Improvement, RR [CI] Treatment Control Tau​2​ = 0.00, I​2​ = 0.0%, p = 0.045 Late treatment 32% 0.68 [0.46-1.01] 21/50 36/58 32% lower risk All studies 32% 0.68 [0.46-1.01] 21/50 36/58 32% lower risk 1 xylitol COVID-19 viral clearance result c19early.org July 2025 Tau​2​ = 0.00, I​2​ = 0.0%, p = 0.045 Favors xylitol Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ RENAISSANCE Cegolon 32% 0.68 [0.46-1.01] viral+ 21/50 36/58 Improvement, RR [CI] Treatment Control Tau​2​ = 0.00, I​2​ = 0.0%, p = 0.045 Late treatment 32% 0.68 [0.46-1.01] 21/50 36/58 32% lower risk All studies 32% 0.68 [0.46-1.01] 21/50 36/58 32% lower risk 1 xylitol COVID-19 peer reviewed studies c19early.org July 2025 Tau​2​ = 0.00, I​2​ = 0.0%, p = 0.045 Effect extraction pre-specified(most serious outcome) Favors xylitol Favors control 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ RENAISSANCE Cegolon 32% 0.68 [0.46-1.01] viral+ 21/50 36/58 Improvement, RR [CI] Treatment Control RENAISSANCE Cegolon 2% 0.98 [0.93-1.03] viral+ 49/50 58/58 RENAISSANCE Cegolon 8% 0.92 [0.85-1.00] viral+ 46/50 58/58 RENAISSANCE Cegolon 18% 0.82 [0.72-0.94] viral+ 41/50 58/58 RENAISSANCE Cegolon 24% 0.76 [0.63-0.91] viral+ 36/50 55/58 RENAISSANCE Cegolon 26% 0.74 [0.59-0.91] viral+ 33/50 52/58 RENAISSANCE Cegolon 32% 0.68 [0.46-1.01] viral+ 21/50 36/58 RENAISSANCE Cegolon 31% 0.69 [0.45-1.05] viral+ 19/50 32/58 RENAISSANCE Cegolon 67% 0.33 [0.17-0.66] viral+ 8/50 28/58 RENAISSANCE Cegolon 77% 0.23 [0.07-0.76] viral+ 3/50 15/58 RENAISSANCE Cegolon 86% 0.14 [0.02-0.88] viral+ 1/50 8/58 Xylitol COVID-19 outcomes c19early.org July 2025 Favors xylitol Favors control