Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury
Q Wu, M Qu, P Zhong, Y Zeng, J Wang, Q Zhang, Ting Wang, D Liu, L Yang, J Zhou, Tong Wang
Bulletin of Experimental Biology and Medicine, doi:10.1007/s10517-022-05407-4
We studied the lung-protective effect and mechanisms of the anti-inflammatory and antioxidant effects of ultra-short-wave diathermy (USWD) in a rat model of LPS-induced acute lung injury. Histological examination of the lung tissues was performed and the levels of oxidative stress-related factors and inflammatory cytokines were measured. It was shown that the lung injury score, the lung wet-to-dry weight ratio (W/D), oxidative stress-related factors malondialdehyde and acyl-CoA synthetase long-chain family member 4 (ACSL4), and inflammatory cytokines were increased after LPS administration, while USWD treatment reduced these parameters. In addition, superoxide dismutase and glutathione peroxidase 4 were decreased in rats with LPS-induced acute lung injury, while USWD therapy up-regulated the expression of these enzymes. Thus, USWD could antagonize lung injury by inhibiting oxidative stress and inflammatory response in rats with acute lung injury. USWD can be a promising adjunctive treatment to counter oxidative stress and inflammation and a potential therapeutic candidate for the treatment of patients with this pathology.
References
Dong, Yuan, Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: Ιnhibition by ST1926, Int. J. Mol. Med,
doi:10.3892/ijmm.2018.3574Imai, Matsuoka, Kumagai, Sakamoto, Koumura, Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis, Curr. Top Microbiol. Immunol,
doi:10.1007/82_2016_508Kellner, Noonepalle, Lu, Srivastava, Zemskov et al., ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS), Adv. Exp. Med. Biol,
doi:10.1007/978-3-319-63245-2_8Lei, Wei, Song, Li, Zhang et al., Cordycepin inhibits LPS-induced acute lung injury by inhibiting inflammation and oxidative stress, Eur. J. Pharmacol,
doi:10.1016/j.ejphar.2017.10.029Li, Cao, Xiao, Shang, Tan et al., Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury, Cell. Death Differ,
doi:10.1038/s41418-020-0528-xLi, Li, Leng, Xiong, Xia, Ferroptosis Is Involved in Diabetes Myocardial Ischemia/Reperfusion Injury Through Endoplasmic Reticulum Stress, DNA Cell. Biol,
doi:10.1089/dna.2019.5097Li, Wu, Wang, Ma, Zhai et al., Dapk1 improves inflammation, oxidative stress and autophagy in LPSinduced acute lung injury via p38MAPK/NF-κB signaling pathway, Mol. Immunol,
doi:10.1016/j.mo-limm.2020.01.014Shields, Gormley, Hare, Short-wave diathermy: current clinical and safety practices, Physiother. Res. Int,
doi:10.1002/pri.259Wang, Deng, Dong, Huang, Li et al., Eriodictyol ameliorates lipopolysaccharide-induced acute lung injury by suppressing the inflammatory COX-2/NLRP3/NF-κB pathway in mice, J. Biochem. Mol. Toxicol,
doi:10.1002/jbt.22434Wang, Feng, Zhao, Zhang, Zhang, Ultrashortwave radiation promotes the recovery of spinal cord injury by inhibiting inflammation via suppression of the MK2/TNF-α pathway, Int. J. Mol. Med,
doi:10.3892/ijmm.2018.3786Wang, Jia, Cao, Feng, Na et al., HUCMSCs transplantation combined with ultrashort wave therapy attenuates neuroinflammation in spinal cord injury through NUR77/NF-κB pathway, Life Sci,
doi:10.1016/j.lfs.2020.118958Xu, Li, Cheng, Yang, Wang, Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion, FASEB J,
doi:10.1096/fj.202001758RYu, Jones, Dean, Laakso, Ultra-shortwave diathermy -a new purported treatment for management of patients with COVID-19, Physiother. Theory Pract,
doi:10.1080/09593985.2020.1757264{ 'indexed': { 'date-parts': [[2023, 11, 20]],
'date-time': '2023-11-20T10:55:43Z',
'timestamp': 1700477743510},
'reference-count': 15,
'publisher': 'Springer Science and Business Media LLC',
'issue': '4',
'license': [ { 'start': { 'date-parts': [[2022, 2, 1]],
'date-time': '2022-02-01T00:00:00Z',
'timestamp': 1643673600000},
'content-version': 'tdm',
'delay-in-days': 0,
'URL': 'https://www.springer.com/tdm'},
{ 'start': { 'date-parts': [[2022, 2, 1]],
'date-time': '2022-02-01T00:00:00Z',
'timestamp': 1643673600000},
'content-version': 'vor',
'delay-in-days': 0,
'URL': 'https://www.springer.com/tdm'}],
'content-domain': {'domain': ['link.springer.com'], 'crossmark-restriction': False},
'published-print': {'date-parts': [[2022, 2]]},
'DOI': '10.1007/s10517-022-05407-4',
'type': 'journal-article',
'created': {'date-parts': [[2022, 2, 17]], 'date-time': '2022-02-17T10:14:57Z', 'timestamp': 1645092897000},
'page': '423-429',
'update-policy': 'http://dx.doi.org/10.1007/springer_crossmark_policy',
'source': 'Crossref',
'is-referenced-by-count': 1,
'title': 'Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat '
'Lung Injury',
'prefix': '10.1007',
'volume': '172',
'author': [ {'given': 'Q.', 'family': 'Wu', 'sequence': 'first', 'affiliation': []},
{'given': 'M.', 'family': 'Qu', 'sequence': 'additional', 'affiliation': []},
{'given': 'P.', 'family': 'Zhong', 'sequence': 'additional', 'affiliation': []},
{'given': 'Y.', 'family': 'Zeng', 'sequence': 'additional', 'affiliation': []},
{'given': 'J.', 'family': 'Wang', 'sequence': 'additional', 'affiliation': []},
{'given': 'Q.', 'family': 'Zhang', 'sequence': 'additional', 'affiliation': []},
{'given': 'Ting', 'family': 'Wang', 'sequence': 'additional', 'affiliation': []},
{'given': 'D.', 'family': 'Liu', 'sequence': 'additional', 'affiliation': []},
{'given': 'L.', 'family': 'Yang', 'sequence': 'additional', 'affiliation': []},
{'given': 'J.', 'family': 'Zhou', 'sequence': 'additional', 'affiliation': []},
{'given': 'Tong', 'family': 'Wang', 'sequence': 'additional', 'affiliation': []}],
'member': '297',
'published-online': {'date-parts': [[2022, 2, 17]]},
'reference': [ { 'issue': '6',
'key': '5407_CR1',
'doi-asserted-by': 'publisher',
'first-page': '3405',
'DOI': '10.3892/ijmm.2018.3574',
'volume': '41',
'author': 'Z Dong',
'year': '2018',
'unstructured': 'Dong Z, Yuan Y. Accelerated inflammation and oxidative stress induced by '
'LPS in acute lung injury: Ιnhibition by ST1926. Int. J. Mol. Med. '
'2018;41(6):3405-3421. doi: https://doi.org/10.3892/ijmm.2018.3574',
'journal-title': 'Int. J. Mol. Med.'},
{ 'key': '5407_CR2',
'doi-asserted-by': 'publisher',
'first-page': '143',
'DOI': '10.1007/82_2016_508',
'volume': '403',
'author': 'H Imai',
'year': '2017',
'unstructured': 'Imai H, Matsuoka M, Kumagai T, Sakamoto T, Koumura T. Lipid '
'Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis. '
'Curr. Top Microbiol. Immunol. 2017;403:143- 170. doi: '
'https://doi.org/10.1007/82_2016_508',
'journal-title': 'Curr. Top Microbiol. Immunol.'},
{ 'key': '5407_CR3',
'doi-asserted-by': 'publisher',
'unstructured': 'Kellner M, Noonepalle S, Lu Q, Srivastava A, Zemskov E, Black S.M. ROS '
'Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute '
'Respiratory Distress Syndrome (ARDS). Adv. Exp. Med. Biol. '
'2017;967:105-137. doi: https://doi.org/10.1007/978-3-319-63245-2_8',
'DOI': '10.1007/978-3-319-63245-2_8'},
{ 'issue': '8',
'key': '5407_CR4',
'doi-asserted-by': 'publisher',
'first-page': '1893',
'DOI': '10.1016/j.bbagen.2017.05.019',
'volume': '1861',
'author': 'GO Latunde-Dada',
'year': '2017',
'unstructured': 'Latunde-Dada GO. Ferroptosis: Role of lipid peroxidation, iron and '
'ferritinophagy. Biochim. Biophys. Acta Gen. Subj. '
'2017;1861(8):1893-1900. doi: '
'https://doi.org/10.1016/j.bbagen.2017.05.019',
'journal-title': 'Biochim. Biophys. Acta Gen. Subj.'},
{ 'key': '5407_CR5',
'doi-asserted-by': 'publisher',
'first-page': '110',
'DOI': '10.1016/j.ejphar.2017.10.029',
'volume': '818',
'author': 'J Lei',
'year': '2018',
'unstructured': 'Lei J, Wei Y, Song P, Li Y, Zhang T, Feng Q, Xu G. Cordycepin inhibits '
'LPS-induced acute lung injury by inhibiting inflammation and oxidative '
'stress. Eur. J. Pharmacol. 2018;818:110-114. doi: '
'https://doi.org/10.1016/j.ejphar.2017.10.029',
'journal-title': 'Eur. J. Pharmacol.'},
{ 'key': '5407_CR6',
'doi-asserted-by': 'publisher',
'first-page': '13',
'DOI': '10.1016/j.molimm.2020.01.014',
'volume': '120',
'author': 'T Li',
'year': '2020',
'unstructured': 'Li T, Wu YN, Wang H, Ma JY, Zhai SS, Duan J. Dapk1 improves '
'inflammation, oxidative stress and autophagy in LPSinduced acute lung '
'injury via p38MAPK/NF-κB signaling pathway. Mol. Immunol. '
'2020;120:13-22. doi: https://doi.org/10.1016/j.molimm.2020.01.014',
'journal-title': 'Mol. Immunol.'},
{ 'issue': '2',
'key': '5407_CR7',
'doi-asserted-by': 'publisher',
'first-page': '210',
'DOI': '10.1089/dna.2019.5097',
'volume': '39',
'author': 'W Li',
'year': '2020',
'unstructured': 'Li W, Li W, Leng Y, Xiong Y, Xia Z. Ferroptosis Is Involved in Diabetes '
'Myocardial Ischemia/Reperfusion Injury Through Endoplasmic Reticulum '
'Stress. DNA Cell. Biol. 2020;39(2):210- 225. doi: '
'https://doi.org/10.1089/dna.2019.5097',
'journal-title': 'DNA Cell. Biol.'},
{ 'issue': '9',
'key': '5407_CR8',
'doi-asserted-by': 'publisher',
'first-page': '2635',
'DOI': '10.1038/s41418-020-0528-x',
'volume': '27',
'author': 'Y Li',
'year': '2020',
'unstructured': 'Li Y, Cao Y, Xiao J, Shang J, Tan Q, Ping F, Huang W, Wu F, Zhang H, '
'Zhang X. Inhibitor of apoptosis-stimulating protein of p53 inhibits '
'ferroptosis and alleviates intestinal ischemia/ reperfusion-induced '
'acute lung injury. Cell. Death Differ. 2020;27(9):2635-2650. doi: '
'https://doi.org/10.1038/s41418-020-0528-x',
'journal-title': 'Cell. Death Differ.'},
{ 'issue': '5',
'key': '5407_CR9',
'doi-asserted-by': 'publisher',
'first-page': '100777',
'DOI': '10.1016/j.cpsurg.2020.100777',
'volume': '57',
'author': 'NT Mowery',
'year': '2020',
'unstructured': 'Mowery NT, Terzian WTH, Nelson AC. Acute lung injury. Curr. Probl. Surg. '
'2020;57(5):100777. doi: https://doi.org/10.1016/j.cpsurg.2020.100777',
'journal-title': 'Curr. Probl. Surg.'},
{ 'issue': '4',
'key': '5407_CR10',
'doi-asserted-by': 'publisher',
'first-page': '191',
'DOI': '10.1002/pri.259',
'volume': '7',
'author': 'N Shields',
'year': '2002',
'unstructured': 'Shields N, Gormley J, O’Hare N. Short-wave diathermy: current clinical '
'and safety practices. Physiother. Res. Int. 2002;7(4):191-202. doi: '
'https://doi.org/10.1002/pri.259',
'journal-title': 'Physiother. Res. Int.'},
{ 'issue': '4',
'key': '5407_CR11',
'doi-asserted-by': 'publisher',
'first-page': '1909',
'DOI': '10.3892/ijmm.2018.3786',
'volume': '42',
'author': 'N Wang',
'year': '2018',
'unstructured': 'Wang N, Feng Z, Zhao W, Zhang Z, Zhang L. Ultrashortwave radiation '
'promotes the recovery of spinal cord injury by inhibiting inflammation '
'via suppression of the MK2/TNF-α pathway. Int. J. Mol. Med. '
'2018;42(4):1909-1916. doi: https://doi.org/10.3892/ijmm.2018.3786',
'journal-title': 'Int. J. Mol. Med.'},
{ 'key': '5407_CR12',
'doi-asserted-by': 'publisher',
'first-page': '118958',
'DOI': '10.1016/j.lfs.2020.118958',
'volume': '267',
'author': 'S Wang',
'year': '2021',
'unstructured': 'Wang S, Jia Y, Cao X, Feng S, Na L, Dong H, Gao J, Zhang L. HUCMSCs '
'transplantation combined with ultrashort wave therapy attenuates '
'neuroinflammation in spinal cord injury through NUR77/NF-κB pathway. '
'Life Sci. 2021;267:118958. doi: '
'https://doi.org/10.1016/j.lfs.2020.118958',
'journal-title': 'Life Sci.'},
{ 'issue': '3',
'key': '5407_CR13',
'doi-asserted-by': 'publisher',
'first-page': 'e22434',
'DOI': '10.1002/jbt.22434',
'volume': '34',
'author': 'X Wang',
'year': '2020',
'unstructured': 'Wang X, Deng R, Dong J, Huang L, Li J, Zhang B. Eriodictyol ameliorates '
'lipopolysaccharide-induced acute lung injury by suppressing the '
'inflammatory COX-2/NLRP3/NF-κB pathway in mice. J. Biochem. Mol. '
'Toxicol. 2020;34(3):e22434. doi: https://doi.org/10.1002/jbt.22434',
'journal-title': 'J. Biochem. Mol. Toxicol.'},
{ 'issue': '12',
'key': '5407_CR14',
'doi-asserted-by': 'publisher',
'first-page': '16262',
'DOI': '10.1096/fj.202001758R',
'volume': '34',
'author': 'Y Xu',
'year': '2020',
'unstructured': 'Xu Y, Li X, Cheng Y, Yang M, Wang R. Inhibition of ACSL4 attenuates '
'ferroptotic damage after pulmonary ischemia-reperfusion. FASEB J. '
'2020;34(12):16262-16275. doi: https://doi.org/10.1096/fj.202001758R',
'journal-title': 'FASEB J.'},
{ 'issue': '5',
'key': '5407_CR15',
'doi-asserted-by': 'publisher',
'first-page': '559',
'DOI': '10.1080/09593985.2020.1757264',
'volume': '36',
'author': 'HP Yu',
'year': '2020',
'unstructured': 'Yu HP, Jones AY, Dean E, Liisa Laakso E. Ultra-shortwave diathermy — a '
'new purported treatment for management of patients with COVID-19. '
'Physiother. Theory Pract. 2020;36(5):559-563. doi: '
'https://doi.org/10.1080/09593985.2020.1757264',
'journal-title': 'Physiother. Theory Pract.'}],
'container-title': 'Bulletin of Experimental Biology and Medicine',
'original-title': [],
'language': 'en',
'link': [ { 'URL': 'https://link.springer.com/content/pdf/10.1007/s10517-022-05407-4.pdf',
'content-type': 'application/pdf',
'content-version': 'vor',
'intended-application': 'text-mining'},
{ 'URL': 'https://link.springer.com/article/10.1007/s10517-022-05407-4/fulltext.html',
'content-type': 'text/html',
'content-version': 'vor',
'intended-application': 'text-mining'},
{ 'URL': 'https://link.springer.com/content/pdf/10.1007/s10517-022-05407-4.pdf',
'content-type': 'application/pdf',
'content-version': 'vor',
'intended-application': 'similarity-checking'}],
'deposited': { 'date-parts': [[2022, 3, 1]],
'date-time': '2022-03-01T01:28:58Z',
'timestamp': 1646098138000},
'score': 1,
'resource': {'primary': {'URL': 'https://link.springer.com/10.1007/s10517-022-05407-4'}},
'subtitle': [],
'short-title': [],
'issued': {'date-parts': [[2022, 2]]},
'references-count': 15,
'journal-issue': {'issue': '4', 'published-print': {'date-parts': [[2022, 2]]}},
'alternative-id': ['5407'],
'URL': 'http://dx.doi.org/10.1007/s10517-022-05407-4',
'relation': {},
'ISSN': ['0007-4888', '1573-8221'],
'subject': ['General Biochemistry, Genetics and Molecular Biology', 'General Medicine'],
'container-title-short': 'Bull Exp Biol Med',
'published': {'date-parts': [[2022, 2]]},
'assertion': [ { 'value': '7 April 2021',
'order': 1,
'name': 'received',
'label': 'Received',
'group': {'name': 'ArticleHistory', 'label': 'Article History'}},
{ 'value': '17 February 2022',
'order': 2,
'name': 'first_online',
'label': 'First Online',
'group': {'name': 'ArticleHistory', 'label': 'Article History'}},
{ 'value': 'This content has been made available to all.',
'name': 'free',
'label': 'Free to read'}]}
