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Home   COVID-19 treatment studies for Bamlanivimab/etesevimab  COVID-19 treatment studies for Bamlaniv../e..  C19 studies: Bamlaniv../e..  Bamlaniv../e..   Select treatmentSelect treatmentTreatmentsTreatments
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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality 80% Improvement Relative Risk Hospitalization 53% Hospitalization/ER 27% primary c19early.org/l Webb et al. Bamlaniv../e.. for COVID-19 EARLY Favors bamlanivimab/e.. Favors control
Real-World Effectiveness and Tolerability of Monoclonal Antibody Therapy for Ambulatory Patients with Early COVID-19
Webb et al., Open Forum Infectious Diseases, doi:10.1093/ofid/ofab331
23 Jun 2021    Source   PDF   Share   Tweet
Retrospective 479 patients treated with bamlanivimab showing lower mortality, hospital admission, and emergency department visits with treatment. Authors incorrectly state that "no other COVID-19 therapies for ambulatory patients have proven effective".
Efficacy is highly variant dependent. In Vitro research suggests a lack of efficacy for omicron [Liu, Sheward, VanBlargan].
risk of death, 79.7% lower, RR 0.20, p = 0.09, treatment 1 of 479 (0.2%), control 57 of 5,536 (1.0%), NNT 122.
risk of hospitalization, 52.7% lower, RR 0.47, p < 0.001, treatment 22 of 479 (4.6%), control 538 of 5,536 (9.7%), NNT 20.
risk of hospitalization/ER, 26.8% lower, RR 0.73, p < 0.001, treatment 65 of 479 (13.6%), control 1,018 of 5,536 (18.4%), NNT 21, odds ratio converted to relative risk, primary outcome.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Webb et al., 23 Jun 2021, retrospective, USA, peer-reviewed, 14 authors.
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