Retrospective 8,634 hospitalized patients in India, showing lower mortality with high-dose vitamin C in unadjusted results. No group details are provided, the text and table appear to show different results, and some numbers do not match.
21 studies are RCTs, which show efficacy with
p=0.0012.
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details; minimal details of groups provided.
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risk of death, 54.2% lower, RR 0.46, p = 0.03, treatment 164 of 8,634 (1.9%), control 10 of 241 (4.1%), NNT 44.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Vishnuram et al., 30 Jun 2021, retrospective, India, peer-reviewed, 5 authors, dosage 4000mg days 1-10.
ROLE OF HIGH DOSE ORAL LIPOSOMAL VITAMIN -C IN REDUCING MORTALITY IN PATIENTS WITH COVID-19
doi:10.36848/IJBAMR/2020/29215.55599
Introduction: Severe cases of COVID-19 are associated with hypoxemic respiratory failure, acute respiratory distress syndrome (ARDS), septic shock, cardiac dysfunction, elevation in multiple inflammatory cytokines, thrombo embolic disease, and/or exacerbation of underlying co morbidities. In addition to pulmonary disease, patients with COVID-19 may also experience cardiac, hepatic, renal, and central nervous system disease. AIM OF THE STUDY ;To describe the role and outcome, of highdose of oral liposomal vitamin C treatment in reducing mortality in Covid-19 patients admitted in Government Medical College
References
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