Retrospective 8,634 hospitalized patients in India, showing lower mortality with high-dose vitamin C in unadjusted results. No group details are provided, the text and table appear to show different results, and some numbers do not match.
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details; minimal details of groups provided.
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risk of death, 54.2% lower, RR 0.46, p = 0.03, treatment 164 of 8,634 (1.9%), control 10 of 241 (4.1%), NNT 44.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Vishnuram et al., 30 Jun 2021, retrospective, India, peer-reviewed, 5 authors, dosage 4000mg days 1-10.
ROLE OF HIGH DOSE ORAL LIPOSOMAL VITAMIN -C IN REDUCING MORTALITY IN PATIENTS WITH COVID-19
doi:10.36848/IJBAMR/2020/29215.55599
Introduction: Severe cases of COVID-19 are associated with hypoxemic respiratory failure, acute respiratory distress syndrome (ARDS), septic shock, cardiac dysfunction, elevation in multiple inflammatory cytokines, thrombo embolic disease, and/or exacerbation of underlying co morbidities. In addition to pulmonary disease, patients with COVID-19 may also experience cardiac, hepatic, renal, and central nervous system disease. AIM OF THE STUDY ;To describe the role and outcome, of highdose of oral liposomal vitamin C treatment in reducing mortality in Covid-19 patients admitted in Government Medical College
References
Arvinte, Singh, Marik, Serum Levels of Vitamin C and Vitamin D in a Cohort of Critically Ill COVID-19 Patients of a North American Community Hospital Intensive Care Unit in May 2020: A Pilot Study. Medicine in Drug Discovery
Chiscano-Camón, Ruiz-Rodriguez, Ruiz-Sanmartin, Roca, Ferrer, Vitamin C levels in patients with SARS-CoV-2-associated acute respiratory distress syndrome, Critical Care
Dr, Ravi Kumar. Dr, gowri sankar indian journal of basic and applied medical research
Holford, Vitamin C for the Prevention and Treatment of Coronavirus, Orthomolecular Medicine News Service
Horby, Lim, Emberson, Dexamethasone in Hospitalized Patients with Covid-19 -Preliminary Report, N Engl J Med
Rasmussen, Vitamin C Evidence for Treating Complications of COVID-19 and other Viral Infections, Orthomolecular Medicine News Service
Zhang, Rao, Li, Zhu, Liu et al., High-dose vitamin C infusion for the treatment of critically ill COVID-19, Pulmonology
