High-Dose Inhaled Nitric Oxide for the Treatment of Spontaneously Breathing Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19) Pneumonia
MD Carlo Valsecchi, MD, Bijan Dario Winterton, Bijan Safaee Fakhr, Ai-Ris Y. Collier, MD Ala Nozari, MD Jamel Ortoleva, MS Shivali Mukerji, MD Lauren E Gibson, MD Ryan W Carroll, MD Shahzad Shaefi, MD, Carolyn Riccardo Pinciroli, Carolyn La Vita, MD Jeanne B Ackman, MD Elizabeth Hohmann, MD Pankaj Arora, MD William H Barth Jr, MD Anjali Kaimal, MD Fumito Ichinose, MD Lorenzo Berra
Obstetrics & Gynecology, doi:10.1097/aog.0000000000004847
for the DELiverly oF iNO (DELFiNO) Network Collaborators* OBJECTIVE: To evaluate whether the use of inhaled nitric oxide (iNO) 200 improves respiratory function.
METHODS: This retrospective cohort study used data from pregnant patients hospitalized with severe bilateral coronavirus disease 2019 (COVID-19) pneumonia at four teaching hospitals between March 2020 and December 2021. Two cohorts were identified: 1) those receiving standard of care alone (SoC cohort) and 2) those receiving iNO 200 for 30 minutes twice daily in addition to standard of care alone (iNO 200 cohort). Inhaled nitric
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