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0 0.5 1 1.5 2+ Hospitalization 38% Improvement Relative Risk Symptomatic case 10% c19early.org/c Vaisi et al. Vitamin C for COVID-19 Prophylaxis Is prophylaxis with vitamin C beneficial for COVID-19? Retrospective 3,955 patients in Iran Lower hospitalization with vitamin C (not stat. sig., p=0.17) Vaisi et al., The Clinical Respiratory J., doi:10.1111/crj.13632 Favors vitamin C Favors control

The association between nutrients and occurrence of COVID-19 outcomes in the population of Western Iran: A cohort study

Vaisi et al., The Clinical Respiratory Journal, doi:10.1111/crj.13632
Vaisi et al., The association between nutrients and occurrence of COVID-19 outcomes in the population of Western Iran: A.., The Clinical Respiratory Journal, doi:10.1111/crj.13632
May 2023   Source   PDF  
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Analysis of nutrient intake and COVID-19 outcomes for 3,996 people in Iran, showing lower risk of COVID-19 hospitalization with sufficient vitamin A, vitamin C, and selenium intake, with statistical significance for vitamin A and selenium.
This is the 60th of 61 COVID-19 controlled studies for vitamin C, which collectively show efficacy with p=0.00000098. 15 studies are RCTs, which show efficacy with p=0.00013.
This study includes vitamin C and vitamin A.
risk of hospitalization, 37.9% lower, HR 0.62, p = 0.17, treatment 2,818, control 1,137, adjusted per study, inverted to make HR<1 favor treatment, sufficient vs. insufficient intake, multivariable, Cox proportional hazards.
risk of symptomatic case, 9.6% lower, HR 0.90, p = 0.71, treatment 2,818, control 1,137, adjusted per study, inverted to make HR<1 favor treatment, sufficient vs. insufficient intake, multivariable, Cox proportional hazards.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Vaisi et al., 11 May 2023, retrospective, Iran, peer-reviewed, 5 authors.
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