DOI record:
{
"DOI": "10.1016/j.bbrc.2020.11.095",
"ISSN": [
"0006-291X"
],
"URL": "http://dx.doi.org/10.1016/j.bbrc.2020.11.095",
"alternative-id": [
"S0006291X20321409"
],
"assertion": [
{
"label": "This article is maintained by",
"name": "publisher",
"value": "Elsevier"
},
{
"label": "Article Title",
"name": "articletitle",
"value": "Identification of antiviral antihistamines for COVID-19 repurposing"
},
{
"label": "Journal Title",
"name": "journaltitle",
"value": "Biochemical and Biophysical Research Communications"
},
{
"label": "CrossRef DOI link to publisher maintained version",
"name": "articlelink",
"value": "https://doi.org/10.1016/j.bbrc.2020.11.095"
},
{
"label": "Content Type",
"name": "content_type",
"value": "article"
},
{
"label": "Copyright",
"name": "copyright",
"value": "© 2020 Elsevier Inc. All rights reserved."
}
],
"author": [
{
"ORCID": "http://orcid.org/0000-0002-4074-9070",
"affiliation": [],
"authenticated-orcid": false,
"family": "Reznikov",
"given": "Leah R.",
"sequence": "first"
},
{
"ORCID": "http://orcid.org/0000-0002-5285-0432",
"affiliation": [],
"authenticated-orcid": false,
"family": "Norris",
"given": "Michael H.",
"sequence": "additional"
},
{
"affiliation": [],
"family": "Vashisht",
"given": "Rohit",
"sequence": "additional"
},
{
"affiliation": [],
"family": "Bluhm",
"given": "Andrew P.",
"sequence": "additional"
},
{
"affiliation": [],
"family": "Li",
"given": "Danmeng",
"sequence": "additional"
},
{
"affiliation": [],
"family": "Liao",
"given": "Yan-Shin J.",
"sequence": "additional"
},
{
"affiliation": [],
"family": "Brown",
"given": "Ashley",
"sequence": "additional"
},
{
"affiliation": [],
"family": "Butte",
"given": "Atul J.",
"sequence": "additional"
},
{
"ORCID": "http://orcid.org/0000-0002-4696-875X",
"affiliation": [],
"authenticated-orcid": false,
"family": "Ostrov",
"given": "David A.",
"sequence": "additional"
}
],
"container-title": "Biochemical and Biophysical Research Communications",
"container-title-short": "Biochemical and Biophysical Research Communications",
"content-domain": {
"crossmark-restriction": true,
"domain": [
"elsevier.com",
"sciencedirect.com"
]
},
"created": {
"date-parts": [
[
2020,
12,
3
]
],
"date-time": "2020-12-03T14:44:42Z",
"timestamp": 1607006682000
},
"deposited": {
"date-parts": [
[
2021,
3,
23
]
],
"date-time": "2021-03-23T15:44:28Z",
"timestamp": 1616514268000
},
"funder": [
{
"DOI": "10.13039/100000002",
"doi-asserted-by": "publisher",
"name": "National Institutes of Health"
},
{
"DOI": "10.13039/100000002",
"doi-asserted-by": "publisher",
"name": "National Institutes of Health"
}
],
"indexed": {
"date-parts": [
[
2023,
12,
26
]
],
"date-time": "2023-12-26T21:17:45Z",
"timestamp": 1703625465935
},
"is-referenced-by-count": 69,
"issued": {
"date-parts": [
[
2021,
1
]
]
},
"language": "en",
"license": [
{
"URL": "https://www.elsevier.com/tdm/userlicense/1.0/",
"content-version": "tdm",
"delay-in-days": 0,
"start": {
"date-parts": [
[
2021,
1,
1
]
],
"date-time": "2021-01-01T00:00:00Z",
"timestamp": 1609459200000
}
}
],
"link": [
{
"URL": "https://api.elsevier.com/content/article/PII:S0006291X20321409?httpAccept=text/xml",
"content-type": "text/xml",
"content-version": "vor",
"intended-application": "text-mining"
},
{
"URL": "https://api.elsevier.com/content/article/PII:S0006291X20321409?httpAccept=text/plain",
"content-type": "text/plain",
"content-version": "vor",
"intended-application": "text-mining"
}
],
"member": "78",
"original-title": [],
"page": "173-179",
"prefix": "10.1016",
"published": {
"date-parts": [
[
2021,
1
]
]
},
"published-print": {
"date-parts": [
[
2021,
1
]
]
},
"publisher": "Elsevier BV",
"reference": [
{
"DOI": "10.2196/19199",
"article-title": "Delivering benefits at speed through real-world repurposing of off-patent drugs: the COVID-19 pandemic as a case in point",
"author": "Rogosnitzky",
"doi-asserted-by": "crossref",
"issue": "2",
"journal-title": "JMIR Public Health Surveill",
"key": "10.1016/j.bbrc.2020.11.095_bib1",
"volume": "6",
"year": "2020"
},
{
"DOI": "10.1016/j.ijantimicag.2020.105949",
"article-title": "Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial",
"author": "Gautret",
"doi-asserted-by": "crossref",
"first-page": "105949",
"issue": "1",
"journal-title": "Int. J. Antimicrob. Agents",
"key": "10.1016/j.bbrc.2020.11.095_bib2",
"volume": "56",
"year": "2020"
},
{
"DOI": "10.1038/s41421-020-0156-0",
"article-title": "Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro",
"author": "Liu",
"doi-asserted-by": "crossref",
"journal-title": "Cell Discov",
"key": "10.1016/j.bbrc.2020.11.095_bib3",
"volume": "6",
"year": "2020"
},
{
"DOI": "10.1038/s41422-020-0282-0",
"article-title": "Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro",
"author": "Wang",
"doi-asserted-by": "crossref",
"first-page": "269",
"issue": "3",
"journal-title": "Cell Res.",
"key": "10.1016/j.bbrc.2020.11.095_bib4",
"volume": "30",
"year": "2020"
},
{
"DOI": "10.1186/1743-422X-2-69",
"article-title": "Chloroquine is a potent inhibitor of SARS coronavirus infection and spread",
"author": "Vincent",
"doi-asserted-by": "crossref",
"journal-title": "Virol. J.",
"key": "10.1016/j.bbrc.2020.11.095_bib5",
"volume": "2",
"year": "2005"
},
{
"author": "Gordon",
"key": "10.1016/j.bbrc.2020.11.095_bib6",
"series-title": "A SARS-CoV-2-Human Protein-Protein Interaction Map reveals Drug Targets and Potential Drug-repurposing",
"year": "2020"
},
{
"DOI": "10.1007/s40265-017-0830-1",
"article-title": "Middle east respiratory syndrome and severe acute respiratory syndrome: current therapeutic options and potential targets for novel therapies",
"author": "Dyall",
"doi-asserted-by": "crossref",
"first-page": "1935",
"issue": "18",
"journal-title": "Drugs",
"key": "10.1016/j.bbrc.2020.11.095_bib7",
"volume": "77",
"year": "2017"
},
{
"DOI": "10.3390/microorganisms8010085",
"article-title": "The use of antimalarial drugs against viral infection",
"author": "D’Alessandro",
"doi-asserted-by": "crossref",
"issue": "1",
"journal-title": "Microorganisms",
"key": "10.1016/j.bbrc.2020.11.095_bib8",
"volume": "8",
"year": "2020"
},
{
"DOI": "10.1126/science.abb2762",
"article-title": "Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2",
"author": "Yan",
"doi-asserted-by": "crossref",
"first-page": "1444",
"issue": "6485",
"journal-title": "Science",
"key": "10.1016/j.bbrc.2020.11.095_bib9",
"volume": "367",
"year": "2020"
},
{
"DOI": "10.1074/jbc.M311191200",
"article-title": "ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis",
"author": "Towler",
"doi-asserted-by": "crossref",
"first-page": "17996",
"issue": "17",
"journal-title": "J. Biol. Chem.",
"key": "10.1016/j.bbrc.2020.11.095_bib10",
"volume": "279",
"year": "2004"
},
{
"DOI": "10.1161/01.HYP.0000146120.29648.36",
"article-title": "Structure-based discovery of a novel angiotensin-converting enzyme 2 inhibitor",
"author": "Huentelman",
"doi-asserted-by": "crossref",
"first-page": "903",
"issue": "6",
"journal-title": "Hypertension",
"key": "10.1016/j.bbrc.2020.11.095_bib11",
"volume": "44",
"year": "2004"
},
{
"DOI": "10.1161/HYPERTENSIONAHA.107.108944",
"article-title": "Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents",
"author": "Hernandez Prada",
"doi-asserted-by": "crossref",
"first-page": "1312",
"issue": "5",
"journal-title": "Hypertension",
"key": "10.1016/j.bbrc.2020.11.095_bib12",
"volume": "51",
"year": "2008"
},
{
"DOI": "10.1177/1087057111413919",
"article-title": "Prediction of off-target effects on angiotensin-converting enzyme 2",
"author": "Kulemina",
"doi-asserted-by": "crossref",
"first-page": "878",
"issue": "8",
"journal-title": "J. Biomol. Screen",
"key": "10.1016/j.bbrc.2020.11.095_bib13",
"volume": "16",
"year": "2011"
},
{
"DOI": "10.4155/fmc-2020-0147",
"article-title": "Tackling SARS-CoV-2: proposed targets and repurposed drugs",
"author": "Joshi",
"doi-asserted-by": "crossref",
"first-page": "1579",
"issue": "17",
"journal-title": "Future Med. Chem.",
"key": "10.1016/j.bbrc.2020.11.095_bib14",
"volume": "12",
"year": "2020"
},
{
"DOI": "10.1016/j.cellsig.2020.109721",
"article-title": "Drugs targeting various stages of the SARS-CoV-2 life cycle: exploring promising drugs for the treatment of covid-19",
"author": "Poduri",
"doi-asserted-by": "crossref",
"first-page": "109721",
"journal-title": "Cell. Signal.",
"key": "10.1016/j.bbrc.2020.11.095_bib15",
"volume": "74",
"year": "2020"
},
{
"DOI": "10.1038/s41586-020-2286-9",
"article-title": "A SARS-CoV-2 protein interaction map reveals targets for drug repurposing",
"author": "Gordon",
"doi-asserted-by": "crossref",
"first-page": "459",
"issue": "7816",
"journal-title": "Nature",
"key": "10.1016/j.bbrc.2020.11.095_bib16",
"volume": "583",
"year": "2020"
},
{
"DOI": "10.1038/s41586-020-2577-1",
"article-title": "Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing",
"author": "Riva",
"doi-asserted-by": "crossref",
"journal-title": "Nature",
"key": "10.1016/j.bbrc.2020.11.095_bib17",
"year": "2020"
},
{
"DOI": "10.1053/j.gastro.2020.05.053",
"article-title": "Famotidine use is associated with improved clinical outcomes in hospitalized COVID-19 patients: a propensity score matched retrospective cohort study",
"author": "Freedberg",
"doi-asserted-by": "crossref",
"journal-title": "Gastroenterology",
"key": "10.1016/j.bbrc.2020.11.095_bib18",
"year": "2020"
},
{
"DOI": "10.1002/jcc.21256",
"article-title": "AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility",
"author": "Morris",
"doi-asserted-by": "crossref",
"first-page": "2785",
"issue": "16",
"journal-title": "J. Comput. Chem.",
"key": "10.1016/j.bbrc.2020.11.095_bib19",
"volume": "30",
"year": "2009"
},
{
"DOI": "10.1038/nature17391",
"article-title": "Crystal structure of the human sigma1 receptor",
"author": "Schmidt",
"doi-asserted-by": "crossref",
"first-page": "527",
"issue": "7600",
"journal-title": "Nature",
"key": "10.1016/j.bbrc.2020.11.095_bib20",
"volume": "532",
"year": "2016"
},
{
"DOI": "10.1080/15548627.2015.1100356",
"article-title": "Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)",
"author": "Klionsky",
"doi-asserted-by": "crossref",
"first-page": "1",
"issue": "1",
"journal-title": "Autophagy",
"key": "10.1016/j.bbrc.2020.11.095_bib21",
"volume": "12",
"year": "2016"
},
{
"key": "10.1016/j.bbrc.2020.11.095_bib22",
"series-title": "R: A Language and Environment for Statistical Computing",
"year": "2014"
},
{
"DOI": "10.1128/JVI.79.6.3846-3850.2005",
"article-title": "Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication",
"author": "Mossel",
"doi-asserted-by": "crossref",
"first-page": "3846",
"issue": "6",
"journal-title": "J. Virol.",
"key": "10.1016/j.bbrc.2020.11.095_bib23",
"volume": "79",
"year": "2005"
},
{
"DOI": "10.1152/ajplung.00025.2020",
"article-title": "Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways",
"author": "Liao",
"doi-asserted-by": "crossref",
"first-page": "L873",
"issue": "5",
"journal-title": "Am. J. Physiol. Lung Cell Mol. Physiol.",
"key": "10.1016/j.bbrc.2020.11.095_bib24",
"volume": "318",
"year": "2020"
},
{
"article-title": "Modulation of (+)-[3H]pentazocine binding to Guinea pig cerebellum by divalent cations",
"author": "Basile",
"first-page": "882",
"issue": "5",
"journal-title": "Mol. Pharmacol.",
"key": "10.1016/j.bbrc.2020.11.095_bib25",
"volume": "42",
"year": "1992"
},
{
"DOI": "10.4161/auto.29309",
"article-title": "Coronavirus NSP6 restricts autophagosome expansion",
"author": "Cottam",
"doi-asserted-by": "crossref",
"first-page": "1426",
"issue": "8",
"journal-title": "Autophagy",
"key": "10.1016/j.bbrc.2020.11.095_bib26",
"volume": "10",
"year": "2014"
},
{
"DOI": "10.1161/01.HYP.0000146120.29648.36",
"article-title": "Structure-based discovery of a novel angiotensin-converting enzyme 2 inhibitor",
"author": "Huentelman",
"doi-asserted-by": "crossref",
"first-page": "903",
"issue": "6",
"journal-title": "Hypertension",
"key": "10.1016/j.bbrc.2020.11.095_bib27",
"volume": "44",
"year": "2004"
},
{
"DOI": "10.1002/jps.2600681134",
"article-title": "Sensitive assay for determination of hydroxyzine in plasma and its human pharmacokinetics",
"author": "Fouda",
"doi-asserted-by": "crossref",
"first-page": "1456",
"issue": "11",
"journal-title": "J. Pharmaceut. Sci.",
"key": "10.1016/j.bbrc.2020.11.095_bib28",
"volume": "68",
"year": "1979"
},
{
"DOI": "10.1002/j.1552-4604.1986.tb02946.x",
"article-title": "Pharmacokinetics of diphenhydramine and a demethylated metabolite following intravenous and oral administration",
"author": "Blyden",
"doi-asserted-by": "crossref",
"first-page": "529",
"issue": "7",
"journal-title": "J. Clin. Pharmacol.",
"key": "10.1016/j.bbrc.2020.11.095_bib29",
"volume": "26",
"year": "1986"
},
{
"DOI": "10.1111/j.1365-2125.2012.04222.x",
"article-title": "Bioavailability and disposition of azelastine and fluticasone propionate when delivered by MP29-02, a novel aqueous nasal spray",
"author": "Derendorf",
"doi-asserted-by": "crossref",
"first-page": "125",
"issue": "1",
"journal-title": "Br. J. Clin. Pharmacol.",
"key": "10.1016/j.bbrc.2020.11.095_bib30",
"volume": "74",
"year": "2012"
},
{
"DOI": "10.1056/NEJMcp2009575",
"article-title": "Severe covid-19",
"author": "Berlin",
"doi-asserted-by": "crossref",
"journal-title": "N. Engl. J. Med.",
"key": "10.1016/j.bbrc.2020.11.095_bib31",
"year": "2020"
},
{
"DOI": "10.1016/j.chest.2020.05.575",
"article-title": "The impact of asthma on mortality in patients with COVID-19",
"author": "Lieberman-Cribbin",
"doi-asserted-by": "crossref",
"journal-title": "Chest",
"key": "10.1016/j.bbrc.2020.11.095_bib32",
"year": "2020"
}
],
"reference-count": 32,
"references-count": 32,
"relation": {},
"resource": {
"primary": {
"URL": "https://linkinghub.elsevier.com/retrieve/pii/S0006291X20321409"
}
},
"score": 1,
"short-title": [],
"source": "Crossref",
"subject": [
"Cell Biology",
"Molecular Biology",
"Biochemistry",
"Biophysics"
],
"subtitle": [],
"title": "Identification of antiviral antihistamines for COVID-19 repurposing",
"type": "journal-article",
"update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy",
"volume": "538"
}