Deficiency of vitamin D is a risk factor of mortality in patients with COVID-19
et al., Revista de Sanidad Militar, doi:10.35366/93773, Apr 2020
Vitamin D for COVID-19
8th treatment shown to reduce risk in
October 2020, now with p < 0.00000000001 from 126 studies, recognized in 18 countries.
No treatment is 100% effective. Protocols
combine treatments.
6,300+ studies for
210+ treatments. c19early.org
|
Retrospective 172 hospitalized COVID-19 patients in Mexico, reporting a very high prevalence of vitamin D deficiency, and significantly higher mortality with low vitamin D levels in unadjusted results.
This is the 2nd of 226 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 115,066,047,903,039,356,928 vigintillion).
This study is excluded in the after exclusion results of meta
analysis:
unadjusted results with no group details.
|
risk of death, 61.7% lower, RR 0.38, p = 0.006, high D levels (≥8ng/mL) 21 of 137 (15.3%), low D levels (<8ng/mL) 14 of 35 (40.0%), NNT 4.1, inverted to make RR<1 favor high D levels (≥8ng/mL), odds ratio converted to relative risk.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Reyes Pérez et al., 30 Apr 2020, retrospective, Mexico, peer-reviewed, 5 authors.
Contact: tort1822@gmail.com.
La deficiencia de vitamina D es un factor de riesgo de mortalidad en pacientes con COVID-19
Revista de Sanidad Militar, doi:10.35366/93773
Introduction: At this moment COVID-19 disease has no specific treatment and there is no vaccine available. This disease has an elevated morbidity-mortality not only in Mexico but worldwide, and it is the reason why it's essential to study factors that could modulate the course of the disease; the role of vitamin D seems to have a fundamental role in immunity when we talk about respiratory infections.
Objective: Determine the association between vitamin D levels and mortality in hospitalized patients with COVID-19 at the Hospital Central Militar México. Material and methods: This study included 172 patients diagnosed with COVID-19 whom serum levels of vitamin 25-(OH)-D were determined. Considering as a case the patients who died from COVID-19 and control patients who survived. Results: Vitamin 25-(OH)-D serum levels in hospitlized patients with COVID-19 were 16.54 ± 7.22 ng/mL. The 95.92% presented vitamin D levels below the ideal range. Patients with vitamin D serum levels bellow 8 ng/mL had 3.68 higher risk of dying from COVID-19. Conclusion: Patients with COVID-19 who require hospitalization were deficient in vitamin D and their serum levels were bellow 8 ng/mL. This is considered a risk factor and therefore increases mortality in the disease caused by COVID-19, reason enough to take several actions such as oral suplementation in order to improve vitamin D serum levels.
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