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Vitamin D levels and clinical outcomes of SARS-CoV-2 Omicron subvariant BA.2 in children: A longitudinal cohort study

Peng et al., Frontiers in Nutrition, doi:10.3389/fnut.2022.960859
Jul 2022  
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Retrospective 116 hospitalized pediatric patients in China, showing accelerated viral clearance early in the disease course, and greater pneumonia lesion improvement with vitamin D sufficiency.
Peng et al., 25 Jul 2022, retrospective, China, peer-reviewed, 5 authors.
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Laurent Hi, William B Grant, Yingxia Liu, Peng D Huang, Denggao Peng, Hua Huang, Zhichao Liu, Yanzhang Gao
Conclusions: Children with vitamin D insu ciency might have poorer clinical outcomes in Omicron subvariant BA. infection, especially in older pediatric patients. Further studies are needed to assess e ectiveness of supplements in reducing the same.
Ethics statement This investigation involving human participants were reviewed and approved by the Ethics Committee of The Third People's Hospital of Shenzhen (Approval Number: 2022-012). Written informed consent for participation was not provided by the participants' legal guardians/next of kin because: Written informed consent from patients participating in this study was waived in accordance with the national legislation and the institutional requirements. Author contributions DP: methodology, investigation, formal analysis, data curation, writing the original draft, and visualization. HH and ZL: investigation, formal analysis, and data curation. YL: conceptualization, investigation, review and editing, and supervision. ZL, YG, and HH: worked on conceptualization, formal analysis, investigation, and data curation. All authors have read and approved the final manuscript version to be submitted. Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher's note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Supplementary material..
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Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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