Analgesics
Antiandrogens
Bromhexine
Budesonide
Cannabidiol
Colchicine
Conv. Plasma
Curcumin
Ensovibep
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lactoferrin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
Paxlovid
Peg.. Lambda
Quercetin
Remdesivir
Vitamins

Other
Feedback
Home
Top
Abstract
All vitamin D studies
Meta analysis
 
Feedback
Home
c19early.org COVID-19 treatment researchVitamin DVitamin D (more..)
Melatonin Meta
Bromhexine Meta Metformin Meta
Budesonide Meta
Cannabidiol Meta Molnupiravir Meta
Colchicine Meta
Conv. Plasma Meta
Curcumin Meta Nigella Sativa Meta
Ensovibep Meta Nitazoxanide Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Peg.. Lambda Meta
Fluvoxamine Meta Quercetin Meta
Hydroxychlor.. Meta Remdesivir Meta
Ivermectin Meta
Lactoferrin Meta

All Studies   Meta Analysis   Recent:  

Vitamin D levels and clinical outcomes of SARS-CoV-2 Omicron subvariant BA.2 in children: A longitudinal cohort study

Peng et al., Frontiers in Nutrition, doi:10.3389/fnut.2022.960859
Jul 2022  
  Twitter
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Retrospective 116 hospitalized pediatric patients in China, showing accelerated viral clearance early in the disease course, and greater pneumonia lesion improvement with vitamin D sufficiency.
Peng et al., 25 Jul 2022, retrospective, China, peer-reviewed, 5 authors.
All Studies   Meta Analysis   Submit Updates or Corrections
This PaperVitamin DAll
Laurent Hi, William B Grant, Yingxia Liu, Peng D Huang, Denggao Peng, Hua Huang, Zhichao Liu, Yanzhang Gao
Conclusions: Children with vitamin D insu ciency might have poorer clinical outcomes in Omicron subvariant BA. infection, especially in older pediatric patients. Further studies are needed to assess e ectiveness of supplements in reducing the same.
Ethics statement This investigation involving human participants were reviewed and approved by the Ethics Committee of The Third People's Hospital of Shenzhen (Approval Number: 2022-012). Written informed consent for participation was not provided by the participants' legal guardians/next of kin because: Written informed consent from patients participating in this study was waived in accordance with the national legislation and the institutional requirements. Author contributions DP: methodology, investigation, formal analysis, data curation, writing the original draft, and visualization. HH and ZL: investigation, formal analysis, and data curation. YL: conceptualization, investigation, review and editing, and supervision. ZL, YG, and HH: worked on conceptualization, formal analysis, investigation, and data curation. All authors have read and approved the final manuscript version to be submitted. Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher's note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Supplementary material..
References
Ai, Wang, He, Zhao, Zhang et al., Antibody evasion of SARS-CoV-2 Omicron BA.1, BA.1.1, BA.2, and BA.3 sub-lineages, Cell Host Microbe, doi:10.1016/j.chom.2022.05.001
Alguwaihes, Sabico, Hasanato, Megdad, Albader, Severe vitamin D deficiency is not related to SARS-CoV-2 infection but may increase mortality risk in hospitalized adults: a retrospective casecontrol study in an Arab Gulf country, Aging Clin Exp Res, doi:10.1007/s40520-021-01831-0
Antoniak, Mackman, Multiple roles of the coagulation protease cascade during virus infection, Blood, doi:10.1182/blood-2013-09-526277
Bayramoglu, Akkoç, Agbaş, Akgün, Yurdakul, The association between vitamin D levels and the clinical severity and inflammation markers in pediatric COVID-19 patients: singlecenter experience from a pandemic hospital, Eur J Pediatr, doi:10.1007/s00431-021-04030-1
Bilezikian, Bikle, Hewison, Lazaretti-Castro, Formenti et al., MECHANISMS IN ENDOCRINOLOGY: Vitamin D and COVID-19, Eur J Endocrinol, doi:10.1530/EJE-20-0665
Chen, Chua, Lu, Chan, Wong et al., Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine, Emerg Microbes Infect, doi:10.1080/22221751.2022.2035195
Duan, Zhu, Tang, Qin, Ct, features of novel coronavirus pneumonia (COVID-19) in children, Eur Radiol, doi:10.1007/s00330-020-06860-3
Greiller, Suri, Jolliffe, Kebadze, Hirsman et al., Vitamin D attenuates rhinovirus-induced expression of intercellular adhesion molecule-1 (ICAM-1) and platelet-activating factor receptor (PAFR) in respiratory epithelial cells, J Steroid Biochem Mol Biol, doi:10.1016/j.jsbmb.2018.11.013
Güven, Gültekin, The effect of high-dose parenteral vitamin D3 on COVID-19-related inhospital mortality in critical COVID-19 patients during intensive care unit admission: an observational cohort study, Eur J Clin Nutr, doi:10.1038/s41430-021-00984-5
Hui, Ho, Cheung, Ng, Ching et al., SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo, Nature, doi:10.1038/s41586-022-04479-6
Kapustova, Petrovicova, Banovcin, Antosova, Bobcakova et al., COVID-19 and the differences in physiological background between children and adults and their clinical consequences, J Clin Endocrinol Metab, doi:10.1210/jc.2015-2175
Karim, Karim, Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic, Lancet
Khare, Godbole, Pawar, Mohan, Pandey et al., Calcitriol [1, 25[OH]2 D3] pre-and post-treatment suppresses inflammatory response to influenza A (H1N1) infection in human lung A549 epithelial cells, Eur J Nutr, doi:10.1007/s00394-012-0449-7
Kim, Lee, Choi, Um, Lee et al., Clinical characteristics of 40 patients infected with the SARS-CoV-2 omicron variant in Korea, J Korean Med Sci, doi:10.3346/jkms.2022.37.e31~
Li, Guan, Wu, Wang, Zhou et al., Rapid spread of SARS-CoV-2 Omicron subvariant BA.2 in a singlesource community outbreak, Clin Infect Dis, doi:10.1093/cid/ciac203
Maghbooli, Sahraian, Ebrahimi, Pazoki, Kafan et al., Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection, Bratisl Lek Listy, doi:10.4149/BLL_2021_119
Martineau, Jolliffe, Hooper, Greenberg, Aloia et al., Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data, Nutrients, doi:10.3390/nu12040988
Paz, Aldunate, Arce, Ferreiro, Cristina et al., Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies, Virus Res, doi:10.1038/s41591-022-01792-5
Peng, Liu, Zheng, Lu, Hou et al., Immunological aspects of SARS-CoV-2 infection and the putative beneficial Frontiers in Nutrition frontiersin, Cell Mol Immunol, doi:10.1038/s41423-022-00853-6
Peng, Zhang, Ji, Pan, Risk factors for redetectable positivity in recovered COVID-19 children, Pediatr Pulmonol, doi:10.1002/ppul.25116
Rössler, Riepler, Bante, Laer, Kimpel, SARS-CoV-2
Salamanna, Maglio, Sartori, Landini, Fini et al., Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study, Int J Mol Sci, doi:10.1016/S0140-6736(22)00327-0
Loading..
Please send us corrections, updates, or comments. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit