The impact of vitamin and mineral supplements usage prior to COVID-19 infection on disease severity and hospitalization
et al., Bosnian Journal of Basic Medical Sciences,
Retrospective survey based analysis of 2,148 COVID-19 recovered patients in Jordan, showing lower risk of severity and hospitalization with vitamin C prophylaxis, without statistical significance.
Although the 25% lower hospitalization is not statistically significant, it is consistent with the significant 19% lower hospitalization [5‑31%]
from meta analysis of the 10 hospitalization results to date
risk of hospitalization, 24.7% lower, RR 0.75, p = 0.08, treatment 52 of 651 (8.0%), control 167 of 1,497 (11.2%), NNT 32, adjusted per study, odds ratio converted to relative risk, multivariable.
risk of severe case, 17.0% lower, RR 0.83, p = 0.18, treatment 66 of 651 (10.1%), control 194 of 1,497 (13.0%), NNT 35, adjusted per study, odds ratio converted to relative risk, multivariable.
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Nimer et al., 28 Feb 2022, retrospective, Jordan, peer-reviewed, survey, 4 authors, study period March 2021 - July 2021.