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The impact of vitamin and mineral supplements usage prior to COVID-19 infection on disease severity and hospitalization

Nimer et al., Bosnian Journal of Basic Medical Sciences, doi:10.17305/bjbms.2021.7009
Feb 2022  
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Hospitalization 24% Improvement Relative Risk Severe case 27% Vitamin B12 for COVID-19  Nimer et al.  Prophylaxis Is prophylaxis with vitamin B12 beneficial for COVID-19? Retrospective 2,148 patients in Jordan (March - July 2021) Lower hospitalization (p=0.15) and severe cases (p=0.06), not sig. c19early.org Nimer et al., Bosnian J. Basic Medical.., Feb 2022 Favorsvitamin B12 Favorscontrol 0 0.5 1 1.5 2+
34th treatment shown to reduce risk in February 2022, now with p = 0.023 from 4 studies.
Lower risk for recovery.
No treatment is 100% effective. Protocols combine treatments.
5,000+ studies for 109 treatments. c19early.org
Retrospective 2,148 COVID-19 recovered patients in Jordan, showing lower risk of severity and hospitalization with vitamin B12 prophylaxis, without statistical significance.
Study covers vitamin A, vitamin C, vitamin D, aspirin, zinc, vitamin B9, vitamin B12, and selenium.
risk of hospitalization, 23.9% lower, RR 0.76, p = 0.15, treatment 35 of 395 (8.9%), control 184 of 1,753 (10.5%), NNT 61, adjusted per study, odds ratio converted to relative risk, multivariable.
risk of severe case, 27.3% lower, RR 0.73, p = 0.06, treatment 40 of 395 (10.1%), control 220 of 1,753 (12.5%), NNT 41, adjusted per study, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Nimer et al., 28 Feb 2022, retrospective, Jordan, peer-reviewed, survey, 4 authors, study period March 2021 - July 2021. Contact: rmnimer@just.edu.jo.
This PaperVitamin B12All
The impact of vitamin and mineral supplements usage prior to COVID-19 infection on disease severity and hospitalization
PhD Refat Nimer, Omar Khabour, Samer Swedan, Hassan Kofahi
Bosnian Journal of Basic Medical Sciences, doi:10.17305/bjbms.2021.7009
The BJBMS publishes an "Advanced online" manuscript format as a free service to authors in order to expedite the dissemination of scientific findings to the research community as soon as possible after acceptance following peer review and corresponding modification (where appropriate). An "Advanced online" manuscript is published online prior to copyediting, formatting for publication and author proofing, but is nonetheless fully citable through its Digital Object Identifier (doi®). Nevertheless, this "Advanced online" version is NOT the final version of the manuscript. When the final version of this paper is published within a definitive issue of the journal with copyediting, full pagination, etc. the new final version will be accessible through the same doi and this "Advanced online" version of the paper will disappear.
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