Dried Cannabis Use, Tobacco Smoking, and COVID-19 Infection: Findings from a Longitudinal Observational Cohort Study

{ 'indexed': {'date-parts': [[2024, 7, 27]], 'date-time': '2024-07-27T00:07:38Z', 'timestamp': 1722038858286}, 'reference-count': 56, 'publisher': 'Research Society on Marijuana', 'content-domain': {'domain': [], 'crossmark-restriction': False}, 'published-print': {'date-parts': [[2024, 7, 26]]}, 'abstract': '<jats:p>Objective: The potential impact of cigarette and cannabis smoking on COVID-19 ' 'infection outcomes is not well understood. We investigated the association between ' 'combustible tobacco use and dried cannabis use with COVID-19 infection in a longitudinal ' 'cohort of community adults. Method: The sample comprised 1,343 participants, originally ' 'enrolled in 2018, who reported their cigarette and cannabis use in 11 assessments over 44 ' 'months, until 2022. COVID-19 infection history were self-reported after the onset of the ' 'pandemic. Univariate and multivariate logistic regression analyses were performed. The ' 'potentially confounding factor of vaccination status was also considered by stratifying data ' 'by booster vaccination self-reporting. Results: Among 1,343 participants, 820 (61.1%) ' 'reported any COVID-19 infection. Dried cannabis use (46.3% of participants, n = 721) was ' 'associated with higher self-reporting of 2+ COVID-19 infections (13.3% vs. 7.3% in non-users, ' 'p = .0004), while tobacco use (18.5% of participants, n = 248) had no significant effect ' '(13.3% vs. 10.0% in no use group, p = .116). When stratified into single or dual substance ' 'use groups, dried cannabis-only use was associated with increased reporting of 1 or 2+ ' 'COVID-19 infections compared to substance non-users, while tobacco-only use and dual use ' 'groups were not significantly different from non-users. To account for differences in ' 'vaccination rates between substance use groups, we found that, among individuals with a ' 'COVID-19 booster vaccine, dried cannabis use was still associated with increased reporting of ' '2+ COVID-19 infections (p = .008). Conclusions: Our study suggests that dried cannabis use is ' 'associated with a higher likelihood of reporting 2+ COVID-19 infections. Although the study ' 'was observational and relied on self-report infection status, our findings support the need ' 'for further investigation into the impact of cannabis use on COVID-19 infection, particularly ' 'studies employing controlled experimental designs.</jats:p>', 'DOI': '10.26828/cannabis/2024/000248', 'type': 'journal-article', 'created': {'date-parts': [[2024, 7, 26]], 'date-time': '2024-07-26T19:24:51Z', 'timestamp': 1722021891000}, 'source': 'Crossref', 'is-referenced-by-count': 0, 'title': 'Dried Cannabis Use, Tobacco Smoking, and COVID-19 Infection: Findings from a Longitudinal ' 'Observational Cohort Study', 'prefix': '10.26828', 'author': [ {'given': 'Nadia', 'family': 'Milad', 'sequence': 'first', 'affiliation': []}, {'given': 'Kyla', 'family': 'Belisario', 'sequence': 'additional', 'affiliation': []}, {'given': 'James', 'family': 'MacKillop', 'sequence': 'additional', 'affiliation': []}, {'given': 'Jeremy', 'family': 'Hirota', 'sequence': 'additional', 'affiliation': []}], 'member': '11370', 'published-online': {'date-parts': [[2024, 7, 26]]}, 'reference': [ { 'key': 'ref0', 'unstructured': 'Centers for Disease Controls. 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