Impact of Famotidine Use on Clinical Outcomes of Hospitalized Patients With COVID-19
MS. Jeffrey F Mather, PhD Richard L Seip, MD Raymond G Mckay
American Journal of Gastroenterology, doi:10.14309/ajg.0000000000000832
INTRODUCTION: To compare outcomes in patients hospitalized with coronavirus (COVID-19) receiving famotidine therapy with those not receiving famotidine.
Study Highlights WHAT IS KNOWN? 3 Despite multiple trials that are currently underway to investigate the safety and efficacy of a large number of possible therapeutic agents, no drug to date has been shown to reduce COVID-19 mortality. 3 It has been postulated that famotidine's effect is achieved via its antagonism or inverse agonism of the histamine-2 receptor, inferring that the SARS-CoV-2 infection that results in COVID-19 is at least partially mediated by pathological histamine release.
COVID-19 Mather et al.
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