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0 0.5 1 1.5 2+ ARDS 100% Improvement Relative Risk Vitamin A for COVID-19  Mandour et al.  Sufficiency Are vitamin A levels associated with COVID-19 outcomes? Prospective study of 60 patients in Egypt (September 2021 - April 2022) Lower ARDS with higher vitamin A levels (p=0.001) c19early.org Mandour et al., The Egyptian J. Bronch.., Jul 2023 Favors vitamin A Favors control

Evaluation of vitamin A and E deficiency with severity of SARS-COV-2 disease: a case–control study

Mandour et al., The Egyptian Journal of Bronchology, doi:10.1186/s43168-023-00210-9, NCT05946499
Jul 2023  
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Case control study with 30 ICU COVID-19 patients, 30 hospitalized non-ICU patients, and 30 matched healthy controls, showing vitamin A levels associated with COVID-19 and severity, with ICU patient levels < hospitalized patients < healthy controls. Authors also show significantly lower risk of ARDS with vitamin A levels above 0.65µg/ml.
risk of ARDS, 99.7% lower, OR 0.003, p < 0.001, cutoff 0.65μg/ml, RR approximated with OR.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Mandour et al., 21 Jul 2023, prospective, Egypt, peer-reviewed, 5 authors, study period September 2021 - April 2022, trial NCT05946499 (history).
Contact: balsam.sherif@kasralainy.edu.eg.
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