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c19early.org COVID-19 treatment researchBamlanivimab/etesevimabBamlaniv../e.. (more..)
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All Studies   Meta Analysis   Recent:  
0 0.5 1 1.5 2+ Symp. case 57% Improvement Relative Risk Symp. case (b) 80% Bamlanivimab/e..  Lilly et al.  Prophylaxis  RCT Is prophylaxis with bamlanivimab/etesevimab beneficial for COVID-19? RCT 965 patients in the USA Fewer symptomatic cases with bamlanivimab/etesevimab (p=0.00021) c19early.org Lilly, Press Release, January 2021 Favors bamlanivimab/e.. Favors control

Lilly's neutralizing antibody bamlanivimab (LY-CoV555) prevented COVID-19 at nursing homes in the BLAZE-2 trial, reducing risk by up to 80 percent for residents

Lilly, Press Release
Jan 2021  
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Press release on the BLAZE-2 trial at nursing homes showing significantly lower symptomatic COVID-19 with treatment.
Efficacy is highly variant dependent. In Vitro research suggests a lack of efficacy for omicron Liu, Sheward, VanBlargan.
risk of symptomatic case, 57.0% lower, RR 0.43, p < 0.001, treatment 483, control 482, group sizes estimated because they were not supplied.
risk of symptomatic case, 80.0% lower, RR 0.20, p < 0.001, treatment 150, control 149, nursing home residents, group sizes estimated because they were not supplied.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lilly et al., 21 Jan 2021, Randomized Controlled Trial, USA, preprint, 1 author.
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