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All Studies   Meta Analysis    Recent:   

Lilly's neutralizing antibody bamlanivimab (LY-CoV555) prevented COVID-19 at nursing homes in the BLAZE-2 trial, reducing risk by up to 80 percent for residents

Lilly, Press Release
Jan 2021  
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Symp. case 57% Improvement Relative Risk Symp. case (b) 80% Bamlanivimab/e..  Lilly et al.  Prophylaxis  RCT Is prophylaxis with bamlanivimab/etesevimab beneficial for COVID-19? RCT 965 patients in the USA Fewer symptomatic cases with bamlanivimab/etesevimab (p=0.00021) c19early.org Lilly, Press Release, January 2021 Favorsbamlanivimab/e.. Favorscontrol 0 0.5 1 1.5 2+
20th treatment shown to reduce risk in May 2021
 
*, now with p = 0.00036 from 21 studies, recognized in 7 countries. Efficacy is variant dependent.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,300+ studies for 75 treatments. c19early.org
Press release on the BLAZE-2 trial at nursing homes showing significantly lower symptomatic COVID-19 with treatment.
Efficacy is highly variant dependent. In Vitro research suggests a lack of efficacy for omicron1-5.
risk of symptomatic case, 57.0% lower, RR 0.43, p < 0.001, treatment 483, control 482, group sizes estimated because they were not supplied.
risk of symptomatic case, 80.0% lower, RR 0.20, p < 0.001, treatment 150, control 149, nursing home residents, group sizes estimated because they were not supplied.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lilly et al., 21 Jan 2021, Randomized Controlled Trial, USA, preprint, 1 author.
This PaperBamlaniv../e..All
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