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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Discharge -12% Improvement Relative Risk Time to discharge -60% Time to viral- -35% c19early.org/k Li et al. Probiotics for COVID-19 LATE TREATMENT Favors probiotics Favors control
The role of probiotics in coronavirus disease-19 infection in Wuhan: A retrospective study of 311 severe patients
Li et al., International Immunopharmacology, doi:10.1016/j.intimp.2021.107531
5 Mar 2021    Source   PDF   Share   Tweet
Retrospective 311 severe condition hospitalized patients in China, 123 treated with probiotics, showing slower viral clearance and recovery with treatment. Authors note that probiotics were able to moderate immunity and decrease the incidence of secondary infections.
The immune effects of probiotics are strain-specific.
risk of no hospital discharge, 11.8% higher, RR 1.12, p = 0.68, treatment 30 of 123 (24.4%), control 41 of 188 (21.8%).
time to discharge, 60.0% higher, relative time 1.60, p < 0.001, treatment 123, control 188.
time to viral-, 35.3% higher, relative time 1.35, p < 0.001, treatment 123, control 188.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Li et al., 5 Mar 2021, retrospective, China, peer-reviewed, 7 authors, average treatment delay 13.0 days.
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Late treatment
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