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All Studies   Meta Analysis    Recent:   

Effect of nanocurcumin supplementation on the severity of symptoms and length of hospital stay in patients with COVID-19: A randomized double-blind placebo-controlled trial

Honarkar Shafie et al., Phytotherapy Research, doi:10.1002/ptr.7374
Jan 2022  
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0 0.5 1 1.5 2+ Hospitalization time 29% Improvement Relative Risk Pulmonary involvement.. 9% no CI Curcumin  Honarkar Shafie et al.  LATE TREATMENT  DB RCT Is late treatment with curcumin beneficial for COVID-19? Double-blind RCT 44 patients in Iran Shorter hospitalization with curcumin (not stat. sig., p=0.22) c19early.org Honarkar Shafie et al., Phytotherapy R.., Jan 2022 Favors curcumin Favors control
Curcumin for COVID-19
14th treatment shown to reduce risk in February 2021
 
*, now known with p = 0.000000015 from 26 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,200+ studies for 70+ treatments. c19early.org
RCT 48 hospitalized patients in Iran, 24 treated with nanocurcumin, showing lower hospitalization time with treatment. The number of patients shown in Table 3 (31 and 27 for each arm) is inconsistent with the number reported as randomized to each arm (24). 160 mg/day nanocurcumin for 6 days. IRCT20131125015536N13.
This study is excluded in meta analysis: unresolved data inconsistency.
hospitalization time, 28.9% lower, relative time 0.71, p = 0.22, treatment mean 6.31 (±5.26) n=23, control mean 8.87 (±8.12) n=21.
relative pulmonary involvement score, 9.1% better, RR 0.91, treatment 23, control 21.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Honarkar Shafie et al., 12 Jan 2022, Double Blind Randomized Controlled Trial, placebo-controlled, Iran, peer-reviewed, 10 authors.
This PaperCurcuminAll
Effect of nanocurcumin supplementation on the severity of symptoms and length of hospital stay in patients with COVID‐19: A randomized double‐blind placebo‐controlled trial
Elaheh Honarkar Shafie, Fateme Taheri, Neda Alijani, Ahmad Reza Okhovvat, Razieh Goudarzi, Nasrin Borumandnia, Leila Aghaghazvini, Seyed Mahdi Rezayat, Saeidreza Jamalimoghadamsiahkali, Mohammad Javad Hosseinzadeh‐attar
Phytotherapy Research, doi:10.1002/ptr.7374
It has been more than a year since the outbreak of COVID-19, and it is still the most critical issue of the healthcare system. Discovering effective strategies to treat infected patients is necessary to decrease the mortality rate. This study aimed to
CONFLICT OF INTEREST The authors declared no conflicts of interest.
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Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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