Role of Sodium Bicarbonate as Adjuvant Treatment of Nonsevere Computed Tomography-identified COVID-19 Pneumonia: A Preliminary Report
Abdelbaset Mohammad Khairy El-Badrawy, Mohamed Saleh, Adel El-Badrawy, Ali Tamer, Mohamed Abd El-Hadidy, Ellatif, Dr Rehab Ahmad Elmorsey, Ahmed A Shokeir
doi:10.4103/ijrc.ijrc_48_21
when China reported the first cluster of cases with a novel coronavirus COVID-19, the disease has been rapidly transmitted to almost all countries worldwide. [1, 2] Owing to the absence of definitive treatment options of COVID-19, investigating alternative adjuvant treatments is appropriate until production of a specific effective medication. The suggestion that sodium bicarbonate (SB) could help to restrain coronavirus 2 (SARS-CoV-2) infection is based upon its anti-influenza properties and its widespread use during the "Spanish flu" pandemic of 1918. SB solution 8.4% is sterile, with a pH >8.6, nonpyrogenic, and is used for the treatment of metabolic acidosis. Bronchoalveolar lavage with SB 8.4% is inhibitory to bacteria, fungi, and tuberculosis in cultures. [3] [4] [5] SB is also a disinfectant against feline calicivirus and coxsackievirus. [6, 7] The severity of COVID-19 in adults is clinically classified into mild, moderate, severe, and critical disease according to the WHO interim guidelines published on May 2020. [8, 9] The location of care as recommended by the WHO depends on the epidemiologic scenario and should be either at a designated COVID-19 health facility, community facility, or where not possible, at home. [10] In the present study, we aimed at investigating the role of SB 8.4% as adjuvant therapy in the treatment of patients with moderate clinical stage and moderate radiological chest
Financial support and sponsorship
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Conflicts of interest There are no conflicts of interest.
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