Is vitamin D level important in pregnant women with COVID-19?
Ahmet Değirmenci, Sertaç Ayçiçek, Fatih Mehmet Fındık, Mulaim Sizer, Azize Pervin Değirmenci, Pelin Değirmenci Ayçiçek, Çiğdem Mermutluoğlu
Journal of Controversies in Obstetrics & Gynecology and Pediatrics, doi:10.51271/jcogp-0035
Aim: The COVID-19 pandemic started in Wuhan City, Hubei Province, China in late December 2019. In our study, we aimed to evaluate the effectiveness of vitamin D levels on the clinic of the disease, laboratory findings, severity of the disease and, length of hospital stay by grouping pregnant patients with a diagnosis of COVID-19 according to their vitamin D levels. Methods: A total of 125 patients were included. According to the vitamin D levels of the patients at the time of hospitalization, two groups were determined as below and above 20ng/ml, which is the limit of vitamin D deficiency. The patients in these two groups were compared in terms of demographic features, clinical findings, laboratory findings, imaging findings, hospitalization times and need for intensive care. Results: When evaluated according to serum 25 hydroxyvitamin D level, patients' fever, pulse, oxygen saturation, the severity of lung involvement in computed tomography, hospitalization there was no statistically significant difference between the groups in terms of duration and need for intensive care. When the laboratory parameters of the patients at hospitalization were compared according to serum 25 hydroxyvitamin D levels, there was no statistically significant difference between the two groups in terms of any laboratory parameter. As a result of the analysis, only lymphocyte count was determined as the independent variable affecting the severity of lung involvement in thorax CT (Computed tomography). As the lymphocyte count decreased, the severity of involvement in thorax CT increased. Conclusion: Our study showed that vitamin D level did not have a significant relationship with any of the parameters related to COVID-19 such as clinical and laboratory findings, severity of the disease and duration of hospitalisation. It is also supported by our study that the decrease in lymphocyte counts is associated with severe COVID-19 disease.
ETHICAL DECLARATIONS Ethics Committee Approval The study was carried out with the permission of the
Informed Consent All patients signed and free and informed consent form.
Referee Evaluation Process Externally peer-reviewed.
Conflict of Interest Statement The authors have no conflicts of interest to declare.
Financial Disclosure The authors declared that this study has received no financial support.
Author Contributions All of the authors declare that they have all participated in the design, execution, and analysis of the paper, and that they have approved the final version.
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'abstract': '<jats:p>Aims: The Covid-19 pandemic started in Wuhan City, Hubei Province, China in late '
'December 2019. In our study, we aimed to evaluate the effectiveness of vitamin D levels on '
'the clinic of the disease, laboratory findings, severity of the disease and, length of '
'hospital stay by grouping pregnant patients with a diagnosis of Covid-19 according to their '
'vitamin D levels.\n'
'Methods: A total of 125 patients were included. According to the vitamin D levels of the '
'patients at the time of hospitalization, two groups were determined as below and above '
'20ng/ml, which is the limit of vitamin D deficiency. The patients in these two groups were '
'compared in terms of demographic features, clinical findings, laboratory findings, imaging '
'findings, hospitalization times and need for intensive care.\n'
'Results: When evaluated according to serum 25 hydroxyvitamin D level, patients’ fever, pulse, '
'oxygen saturation, the severity of lung involvement in computed tomography, hospitalization '
'there was no statistically significant difference between the groups in terms of duration and '
'need for intensive care. When the laboratory parameters of the patients at hospitalization '
'were compared according to serum 25 hydroxyvitamin D levels, there was no statistically '
'significant difference between the two groups in terms of any laboratory parameter. As a '
'result of the analysis, only lymphocyte count was determined as the independent variable '
'affecting the severity of lung involvement in thorax CT (Computed tomography). As the '
'lymphocyte count decreased, the severity of involvement in thorax CT increased.\n'
'Conclusion: Our study showed that vitamin D level did not have a significant relationship '
'with any of the parameters related to Covid-19 such as clinical and laboratory findings, '
'severity of the disease and duration of hospitalisation. It is also supported by our study '
'that the decrease in lymphocyte counts is associated with severe Covid-19 disease.</jats:p>',
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