Efficacy of ursodeoxycholic acid in the prevention and treatment of COVID-19 in patients with chronic hepatitis B

Cui et al., Journal of Clinical Hepatology, doi:10.12449/JCH240309

Mar 2024

Retrospective 215 patients with chronic hepatitis B in China, showing lower risk of COVID-19 infection, milder symptoms, and faster recovery with ursodeoxycholic acid (UDCA) treatment.

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recovery time >7 days, 47.8% lower, RR 0.52, p = 0.010, treatment 13 of 64 (20.3%), control 51 of 131 (38.9%), NNT 5.4, propensity score matching.

risk of case, 83.0% lower, OR 0.17, p = 0.001, treatment 78, control 137, adjusted per study, propensity score matching, multivariable, RR approximated with OR.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates

Cui et al., 20 Mar 2024, retrospective, China, peer-reviewed, 5 authors.

This Paper UDCA All

，缩短恢复时间，在防治 COVID-19 方面具有重要价值。关键词：乙型肝炎，慢性；新型冠状病毒；熊去氧胆酸；倾向性评分基金项目：北京市自然科学基金(7212053) Efficacy of ursodeoxycholic acid in the prevention and treatment of COVID-19 in patients with chronic hepatitis B

Cui Xinyu, ， Li, ， Zhu, ， Lin

doi:10.12449/JCH240309

摘要：目的探讨慢性乙型肝炎患者服用熊去氧胆酸后对新型冠状病毒感染

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崔心宇, 朱娜, 效果分 []. 临床肝胆病杂志

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