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All Studies   Meta Analysis    Recent:   

Budesonide for COVID-19: real-time meta analysis of 15 studies

Covid Analysis
Jun 2024  
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Budesonide for COVID-19
18th treatment shown to reduce risk in April 2021
 
*, now known with p = 0.0000011 from 15 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,200+ studies for 70+ treatments. c19early.org
Statistically significant lower risk is seen for mortality, ICU admission, hospitalization, progression, recovery, and cases. 11 studies from 11 independent teams in 8 countries show significant improvements.
Meta analysis using the most serious outcome reported shows 28% [18‑36%] lower risk. Results are similar for Randomized Controlled Trials, higher quality studies, and peer-reviewed studies. Early treatment is more effective than late treatment.
Results are very robust — in exclusion sensitivity analysis 11 of 15 studies must be excluded to avoid finding statistically significant efficacy in pooled analysis.
4 RCTs with 916 patients have not reported results (up to 4 years late).
Inhaler technique and adherence may significantly affect outcomes1.
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments are more effective.
All data to reproduce this paper and sources are in the appendix. Yu present another meta analysis for budesonide, showing significant improvement for recovery.
Covid Analysis et al., Jun 2024, preprint, 1 author.
This PaperBudesonideAll
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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