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The Effect of Weekly 50,000 IU Vitamin D3 Supplements on the Serum Levels of Selected Cytokines Involved in Cytokine Storm: A Randomized Clinical Trial in Adults with Vitamin D Deficiency

Bader et al., Nutrients, doi:10.3390/nu15051188
Feb 2023  
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RCT 100 patients in Jordan, showing that high-dose cholecalciferol (50,000 IU/week) significantly increased IL-6, indicating that high weekly doses could have a negative effect for cytokine storm with COVID-19. Other studies have found no significant difference in IL-6 El Hajj, Mousa.
Bader et al., 27 Feb 2023, Jordan, peer-reviewed, 10 authors, study period October 2020 - December 2020.
Contact: (corresponding author).
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The Effect of Weekly 50,000 IU Vitamin D3 Supplements on the Serum Levels of Selected Cytokines Involved in Cytokine Storm: A Randomized Clinical Trial in Adults with Vitamin D Deficiency
Dana A Bader, Anas Abed, Beisan A Mohammad, Ahmad Aljaberi, Ahmad Sundookah, Maha Habash, Ahmad R Alsayed, Mohammad Abusamak, Sami Al-Shakhshir, Mahmoud Abu-Samak
Nutrients, doi:10.3390/nu15051188
Abu-Samak, M. The Effect of Weekly 50,000 IU Vitamin D 3 Supplements on the Serum Levels of Selected Cytokines Involved in Cytokine Storm: A Randomized Clinical Trial in Adults with Vitamin D Deficiency.
Conflicts of Interest: The authors declare no conflict of interest.
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