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All Studies   Meta Analysis    Recent:   

The Effect of Vitamin D treatment on COVID 19- Patients, an Inverted Propensity Score Weighting (IPSW), and Inverted Probability of Treatment Weighting (IPTW) Analyzed Study

Wadi Al Ramahi et al., The International Arabic Journal of Antimicrobial Agents, doi:10.3823/862
Mar 2022  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
*, now known with p < 0.00000000001 from 120 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments.
Retrospective study comparing 847 patients receiving ≤149,000IU vitamin D and 170 receiving ≥150,000IU, showing no significant differences, however the result may not be very meaningful - membership in the higher cumulative dose group requires longer hospitalization, e.g., patients discharged shortly after admission (a positive outcome) could not be in the higher cumulative dose group.
Wadi Al Ramahi et al., 7 Mar 2022, peer-reviewed, 15 authors.
This PaperVitamin DAll
The Effect of Vitamin D treatment on COVID 19- Patients, an Inverted Propensity Score Weighting (IPSW), and Inverted Probability of Treatment Weighting (IPTW) Analyzed Study
Jamal Wadi Al Ramahi, Nour Hasan, Amal Matar, Ma'en Maher Al-Ali, Lara Abdulhadi, Dania Abu Kaf, Waseem Saadeh, Nour Hamdan, Hassan Abukhalaf, Mohamed Gharaibeh, Hanadi Hamadallah, Ala'a Bader, Mohammad Atout, Sae’ed Moh. Mar’i, Tamer Alhamed
The International Arabic Journal of Antimicrobial Agents, doi:10.3823/862
Background: Vitamin D3 (1,25(OH) 2 cholecalciferol) as a treatment for COVID 19 patients is being disputed, and a clear clinical benefit is not being confirmed. Methods: A retrospective evaluation for COVID-19 patients who were treated with various cumulative doses of vitamin D. Data was extracted from the COVID-19 database, it included patients admitted to three hospitals in Amman, Jordan. Characteristics of patients were tabulated and compared for all-cohort, and propensity score index (PSI) adjustment. The comparison was based on two vitamin D strata (≤ 149,000 i.u. and > 150,000 i.u.). Logistic regression analysis was utilized to predict recovery, the need for oxygen, and all-cause mortality for all-cohort, IPSW, and IPTW patients, based on vitamin D cumulative doses during their hospital stay. Results: 1131 all-cohort and 768 PSI-adjusted patients were recruited. Except for antibiotics and antivirals, all other characteristics were balanced (P = NS). There were 1017 patients on vitamin D, 847 received cumulative ≤ 149,000 i.u., and 170 patients received cumulative dose
The Journal is an open access peer-reviewed journal that publishes scientific papers about all aspects of antimicrobials. The journal will publish original research articles, reviews, brief reports and case reports dealing with basic and clinical antibacterial agents, antiviral, antiprotozoals, antituberculuous, antifungal and antihelminthes agents. All manuscripts must be prepared in English, and are subject to a rigorous and fair peer-review process. Accepted papers will immediately appear online. The journal aims to advance the knowledge, attitude and the research of chemotherapy in the Arabic world in cooperation with international, national scientific and public societies as well as research centers with similar aims and objectives.
Alanagreh, Alzoughool, Atoum, The human coronavirus disease COVID-19: its origin, characteristics, and insights into potential drugs and its mechanisms, Pathogens
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Late treatment
is less effective
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