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Association of SARS-CoV-2 infection with physical activity domains and types

Vanhelst et al., Scientific Reports, doi:10.1038/s41598-023-46162-4, NCT03335644
Nov 2023  
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Exercise for COVID-19
9th treatment shown to reduce risk in October 2020
 
*, now with p < 0.00000000001 from 66 studies.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,500+ studies for 81 treatments. c19early.org
Retrospective 22,165 adults in the French NutriNet-Santé cohort showing higher levels of total physical activity, vigorous activity, leisure-time activity, household activity, outdoor activity, and indoor activity during the COVID-19 lockdown period were associated with lower risk of SARS-CoV-2 infection. Results show the odds ratios per 30 minute or 250 MET increment per week.
Vanhelst et al., 6 Nov 2023, France, peer-reviewed, 65 authors, study period 1 April, 2020 - 12 May, 2020, trial NCT03335644 (history). Contact: jeremy.vanhelst@eren.smbh.univ-paris13.fr.
This PaperExerciseAll
Association of SARS-CoV-2 infection with physical activity domains and types
Jérémy Vanhelst, Bernard Srour, Laurent Bourhis, Hélène Charreire, Charlotte Mélanie Verdotdeschasaux-Tanguy, Nathalie Druesne-Pecollo, Fabien Szabo De Edelenyi, Julien Allègre, Benjamin Allès, Valérie Deschamps, Alice Bellicha, Leopold K Fezeu, Pilar Galan, Chantal Julia, Emmanuelle Kesse-Guyot, Serge Hercberg, Nathalie Bajos, Gianluca Severi, Marie Zins, Xavier De Lamballerie, Fabrice Carrat, Jean-Michel Oppert, Mathilde Touvier, Hélène Blanché, Jean-François Deleuze, Clovis Lusivika-Nzinga, Gregory Pannetier, Nathanael Lapidus, Isabelle Goderel, Céline Dorival, Jérôme Nicol, Olivier Robineau, Sofiane Kab, Adeline Renuy, Stéphane Le-Got, Céline Ribet, Mireille Pellicer, Emmanuel Wiernik, Marcel Goldberg, Fanny Artaud, Pascale Gerbouin-Rérolle, Mélody Enguix, Camille Laplanche, Roselyn Gomes-Rima, Lyan Hoang, Emmanuelle Correia, Alpha Amadou Barry, Nadège Senina, Younes Esseddik, Mélanie Deschasaux, Jean-Marc Sébaoun, Jean-Christophe Beaudoin, Laetitia Gressin, Valérie Morel, Ouissam Ouili, Laetitia Ninove, Stéphane Priet, Paola Mariela Saba Villarroel, Toscane Fourié, Souand Mohamed Ali, Abdenour Amroun, Morgan Seston, Nazli Ayhan, Boris Pastorino
Scientific Reports, doi:10.1038/s41598-023-46162-4
Study Groups
Author contributions Designed research, contributed to the conception and interpretation of the analyses: H.C., C.V., M.D., N.D.P., J.A., B.A., V.D., A.B., L.F., P.G., C.J., E.K.G., S.H., N.B., G.S., M.Z., X.L., F.C., J.M.O. and M.T. Statistical analysis: B.S., L.B., F.S.E. Drafted the manuscript. J.V. All authors critically revised the manuscript, and approved the final version of the manuscript to be submitted. Competing interests Prof. Fabrice Carrat reports personal fees from Imaxio and Sanofi, outside the submitted work. All other authors declare no competing interest. Additional information Supplementary Information The online version contains supplementary material available at https:// doi. org/ 10. 1038/ s41598-023-46162-4. Correspondence and requests for materials should be addressed to J.V. Reprints and permissions information is available at www.nature.com/reprints.
References
Ainsworth, Compendium of physical activities: A second update of codes and MET values, Med. Sci. Sports Exerc
Andreeva, Comparison of dietary intakes between a large online cohort study (Etude NutriNet-Santé) and a nationally representative cross-sectional study (Etude Nationale Nutrition Santé) in France: Addressing the issue of generalizability in E-epidemiology, Am. J. Epidemiol
Arem, Leisure time physical activity and mortality: A detailed pooled analysis of the dose-response relationship, JAMA Intern. Med
Bull, World Health Organization 2020 guidelines on physical activity and sedentary behaviour, Br. J. Sports Med
Carrat, Corrigendum to: Antibody status and cumulative incidence of SARS-CoV-2 infection among adults in three regions of France following the first lockdown and associated risk factors: A multicohort study, Int. J. Epidemiol
Carrat, Incidence and risk factors of COVID-19-like symptoms in the French general population during the lockdown period: A multi-cohort study, BMC Infect. Dis
Charreire, Correlates of changes in physical activity and sedentary behaviors during the COVID-19 lockdown in France: The NutriNet-Santé cohort study, Int. J. Environ. Res. Public Health
Chastin, Effects of regular physical activity on the immune system, vaccination and risk of community-acquired infectious disease in the general population: Systematic review and meta-analysis, Sports Med
Chen, Causal relationship between physical activity, leisure sedentary behaviors and COVID-19 risk: A Mendelian randomization study, J. Transl Med
Cho, Physical activity and the risk of COVID-19 infection and mortality: A nationwide population-based case-control study, J. Clin. Med
Craig, International physical activity questionnaire: 12-country reliability and validity, Med. Sci. Sports Exerc
Deschasaux-Tanguy, Nutritional risk factors for SARS-CoV-2 infection: A prospective study within the NutriNet-Santé cohort, BMC Med
Ekelund, Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: Systematic review and harmonised meta-analysis, BMJ
Ezzatvar, Ramírez-Vélez, Izquierdo, Garcia-Hermoso, Physical activity and risk of infection, severity and mortality of COVID-19: A systematic review and non-linear dose-response meta-analysis of data from 1,853,610 adults, Br. J. Sports Med, doi:10.1136/bjsports-2022-105733
Fiuza-Luces, Exercise benefits in cardiovascular disease: Beyond attenuation of traditional risk factors, Nat. Rev. Cardiol
Henry, Vigorous physical activity provides protection against all-cause deaths among adults patients with nonalcoholic fatty liver disease (NAFLD), Aliment. Pharmacol. Ther, doi:10.1111/apt.17308
Hercberg, The Nutrinet-Santé Study: A web-based prospective study on the relationship between nutrition and health and determinants of dietary patterns and nutritional status, BMC Public Health
Jordan, Adab, Cheng, Covid-19: Risk factors for severe disease and death, BMJ
Keaney, Kilding, Merien, Dulson, The impact of sport related stressors on immunity and illness risk in team-sport athletes, J. Sci. Med. Sport
Kesse-Guyot, Lessons learned from methodological validation research in E-epidemiology, JMIR Public Health Surveill
Lancaster, Febbraio, The immunomodulating role of exercise in metabolic disease, Trends Immunol
Lassale, Validity of web-based self-reported weight and height: Results of the Nutrinet-Santé study, J. Med. Internet Res
Lee, Physical activity and the risk of SARS-CoV-2 infection, severe COVID-19 illness and COVID-19 related mortality in South Korea: A nationwide cohort study, Br. J. Sports Med
Mehraeen, Predictors of mortality in patients with COVID-19-a systematic review, Eur. J. Integr. Med
Nieman, Henson, Austin, Sha, Upper respiratory tract infection is reduced in physically fit and active adults, Br. J. Sports Med, doi:10.1038/s41598-023-46162-4www.nature.com/scientificreports/
Nieman, Sakaguchi, Physical activity lowers the risk for acute respiratory infections: Time for recognition, J. Sport Health Sci
Nieman, Wentz, The compelling link between physical activity and the body's defense system, J. Sport Health Sci
Orkaby, Forman, Physical activity and CVD in older adults: An expert's perspective, Expert Rev. Cardiovasc. Ther
Patel, Comparative performance of five commercially available serologic assays to detect antibodies to SARS-CoV-2 and identify individuals with high neutralizing titers, J. Clin. Microbiol
Sallis, Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: A study in 48 440 adult patients, Br. J. Sports Med
Shephard, Limits to the measurement of habitual physical activity by questionnaires, Br. J. Sports Med
Simpson, Kunz, Agha, Graff, Chapter fifteen: Exercise and the regulation of immune functions
Tehrani, Performance of nucleocapsid and spike-based SARS-CoV-2 serologic assays, PLoS One
Tian, Predictors of mortality in hospitalized COVID-19 patients: A systematic review and meta-analysis, J. Med. Virol
Vergnaud, Agreement between web-based and paper versions of a socio-demographic questionnaire in the NutriNet-Santé study, Int. J. Public Health
Xu, A meta-analysis on the risk factors adjusted association between cardiovascular disease and COVID-19 severity, BMC Public Health
Zhang, Physical activity and COVID-19: An observational and Mendelian randomisation study, J. Glob. Health
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All other authors declare no competing interest.', 'order': 1, 'name': 'Ethics', 'group': {'name': 'EthicsHeading', 'label': 'Competing interests'}}], 'article-number': '19187'}
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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