Summary of COVID-19 smoking studies


1,811 patient smoking long COVID study: 37% lower long COVID (p=0.14).
Retrospective 1,811 COVID-19 patients in the UK, showing lower risk of self-reported long COVID with no smoking in the month before infection, not reaching statistical significance (p=0.14).

Apr 2022, medRxiv, https://www.medrxiv.org/content/10.1101/2022.04.12.22273792, https://c19p.org/paulsm

7,846 patient smoking prophylaxis study: 3% lower mortality (p=0.8).
Retrospective 10,074 hospitalized veterans with COVID-19 in the USA, showing higher risk of mortality for former smokers and no significant difference for current smokers.

Oct 2021, Nicotine & Tobacco Research, https://academic.oup.com/ntr/advance-article/doi/10.1093/ntr/ntab223/6409756?login=false, https://c19p.org/razjouyansm

1,000 patient smoking early treatment study: 134% more cases (p<0.0001).
Retrospective 1,000 frontline healthcare workers in South Africa showing higher risk of COVID-19 for non-smokers.

Mar 2024, Vaccines, https://www.mdpi.com/2076-393X/12/3/329, https://c19p.org/mockeliunas

5,197 patient smoking prophylaxis study: 72% more cases (p=0.02).
Retrospective 5,197 Greek adults over 65. After adjustment for confounders, COVID-19 infection was independently associated with poor sleep, low physical activity, low Mediterranean diet adherence, living in urban areas, smoking, obesity, depression, anxiety, stress, and poor health-related quality of life.

Nov 2023, Diseases, https://www.mdpi.com/2079-9721/11/4/165, https://c19p.org/pavlidousm

10,000 patient smoking prophylaxis study: 82% more cases (p<0.0001).
Retrospective 10,000 adults in Qatar, showing lower risk of COVID-19 cases with smoking. Authors do not analyze COVID-19 severity.

Nov 2023, Nutrients, https://www.mdpi.com/2072-6643/16/7/1037, https://c19p.org/akbar2sm

441 patient smoking prophylaxis study: 270% more cases (p<0.0001).
Case control analysis with 149 multiple sclerosis patients and 292 matched controls in Italy, showing lower risk of COVID-19 cases with smoking.

Feb 2023, J. Neurology, https://link.springer.com/10.1007/s00415-023-11618-0, https://c19p.org/montinism