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0 0.5 1 1.5 2+ Improvement in Ct value 6% Improvement Relative Risk Improvement in Ct value (b) 11% c19early.org/p Sulistyani et al. Povidone-Iod.. for COVID-19 RCT EARLY Favors povidone-iodine Favors control
The effects of mouth rinsing and gargling with mouthwash containing povidone-iodine and hydrogen peroxide on the cycle threshold value of Severe Acute Respiratory Syndrome Coronavirus 2: A randomized controlled trial of asymptomatic and mildly symptomatic patients
Sulistyani et al., F1000Research, doi:10.12688/f1000research.110843.1 (date from earlier preprint)
15 Mar 2022    Source   PDF   DATA   Share   Tweet
Small mouth rinsing and gargling RCT with 15 1% PVP-I, 12 0.5% PVP-I, 15 3% hydrogen peroxide, 12 1.5% hydrogen peroxide, and 15 water patients, showing rapid improvement in Ct value in all groups, and no significant differences between groups.
relative improvement in Ct value, 6.3% better, RR 0.94, p = 0.74, treatment mean 12.905 (±5.96) n=15, control mean 12.088 (±7.38) n=15, 1% PVP-I vs. water, day 5.
relative improvement in Ct value, 11.3% better, RR 0.89, p = 0.54, treatment mean 13.628 (±6.28) n=15, control mean 12.088 (±7.38) n=15, 0.5% PVP-I vs. water, day 5.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Sulistyani et al., 15 Mar 2022, Single Blind Randomized Controlled Trial, Indonesia, peer-reviewed, 9 authors, study period July 2021 - September 2021.
Contact: liliesdwi_s@yahoo.co.id.
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