Preliminary observation of the use of sodium bicarbonate solution as an adjunct in the treatment of coronavirus 2019 disease (COVID-19): prognosis improvement in patients requiring intensive care
et al., Brazilian Journal of Development, doi:10.34117/bjdv7n12-039
, Preliminary observation of the use of sodium bicarbonate solution as an adjunct in the treatment of.., Brazilian Journal of Development, doi:10.34117/bjdv7n12-039
Analysis of 76 ICU patients in Brazil, 44 treated with bronchoalveolar lavage using 3% sodium bicarbonate, showing significantly lower mortality with treatment.Bronchoalveolar lavage with 10ml of sodium bicarbonate solution directly into the tube (closed circuit), 500μl for each lung segment, followed by aspiration of the solution, performed every 6 hours for 7 days.
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risk of death, 75.8% lower, RR 0.24, p < 0.001, treatment 6 of 44 (13.6%), control 18 of 32 (56.2%), NNT 2.3.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Soares et al., 29 Dec 2021, prospective, Brazil, peer-reviewed, 17 authors, study period December 2020 - May 2021.
Late treatment
is less effective
is less effective
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