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All Studies   Meta Analysis   Recent:  
0 0.5 1 1.5 2+ Mortality -3% Improvement Relative Risk Death/ICU -3% Famotidine  Shoaibi et al.  LATE TREATMENT Is late treatment with famotidine beneficial for COVID-19? Retrospective 28,636 patients in the USA No significant difference in outcomes seen c19early.org Shoaibi et al., American J. Gastroente.., Sep 2020 Favors famotidine Favors control

Comparative Effectiveness of Famotidine in Hospitalized COVID-19 Patients

Shoaibi et al., American Journal of Gastroenterology, doi:10.14309/ajg.0000000000001153 (date from preprint)
Sep 2020  
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Retrospective 1,816 famotidine users and 26,820 non-users hospitalized for COVID-19 in the USA, showing no significant differences with treatment.
risk of death, 3.0% higher, RR 1.03, p = 0.67, treatment 1,816, control 26,820.
risk of death/ICU, 3.0% higher, RR 1.03, p = 0.62, treatment 1,816, control 26,820.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Shoaibi et al., 24 Sep 2020, retrospective, database analysis, USA, peer-reviewed, 5 authors.
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This PaperFamotidineAll
Comparative Effectiveness of Famotidine in Hospitalized COVID-19 Patients
PhD Azza Shoaibi, PharmD Stephen Fortin, MS Rachel Weinstein, Jesse A Berlin, PhD Patrick Ryan
doi:10.1101/2020.09.23.20199463
All authors contributed to the conceptualization and design of the study. SF authored the protocol of the study design, AS implemented the statistical analysis, RW, PBR and JB reviewed and approved the study diagnostics and results. AS drafted the manuscript and all coauthors reviewed and contributed to the manuscript writing. .
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Mather, Seip, Mckay, Impact of Famotidine Use on Clinical Outcomes of Hospitalized Patients With COVID-19, Official journal of the American College of Gastroenterology| ACG
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Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of over 100,000 datapoints from thousands of papers. Community updates help ensure high accuracy. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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