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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Mortality -8% Improvement Relative Risk Oxygen time 27% Hospitalization time 29% c19early.org/ns Setayesh et al. IRCT20200330046899N1 Nigella Sativa RCT LATE Favors nigella sativa Favors control
Efficacy of a Persian herbal medicine compound on coronavirus disease 2019 (COVID-19): a randomized clinical trial
Setayesh et al., Integrative Medicine Research, doi:10.1016/j.imr.2022.100869, IRCT20200330046899N1
3 Jun 2022    Source   PDF   Share   Tweet
Small RCT 41 patients treated with nigella sativa, glycyrrhiza glabra, punica granatum, and rheum palmatum, and 41 control patients, showing shorter hospitalization with treatment.
risk of death, 7.9% higher, RR 1.08, p = 1.00, treatment 1 of 38 (2.6%), control 1 of 41 (2.4%).
oxygen time, 26.8% lower, relative time 0.73, p = 0.007, treatment mean 3.0 (±1.6) n=38, control mean 4.1 (±1.9) n=41.
hospitalization time, 28.7% lower, relative time 0.71, p < 0.001, treatment mean 5.7 (±1.9) n=38, control mean 8.0 (±1.8) n=41.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Setayesh et al., 3 Jun 2022, Randomized Controlled Trial, Iran, peer-reviewed, mean age 59.1, 7 authors, study period June 2020 - September 2020, this trial uses multiple treatments in the treatment arm (combined with glycyrrhiza glabra, punica granatum, and rheum palmatum) - results of individual treatments may vary, trial IRCT20200330046899N1.
Contact: hasheminasab@zaums.ac.ir, hashemifa67@gmail.com.
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This PaperNigella SativaAll
Late treatment
is less effective
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