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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality 49% Improvement Relative Risk Metformin for COVID-19  Servais et al.  Prophylaxis Is prophylaxis with metformin beneficial for COVID-19? Retrospective study in Belgium (March - May 2020) Lower mortality with metformin (p=0.0018) c19early.org Servais et al., Annals of Endocrinology, Dec 2022 Favors metformin Favors control

Mortality-related risk factors of inpatients with diabetes and COVID-19: a multicenter retrospective study in Belgium

Servais et al., Annals of Endocrinology, doi:10.1016/j.ando.2023.08.002
Dec 2022  
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Metformin for COVID-19
3rd treatment shown to reduce risk in July 2020
 
*, now known with p < 0.00000000001 from 88 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,000+ studies for 60+ treatments. c19early.org
Retrospective 375 hospitalized diabetes patients in Belgium, showing lower risk of COVID-19 mortality with metformin use.
risk of death, 49.0% lower, HR 0.51, p = 0.002, adjusted per study, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Servais et al., 7 Dec 2022, retrospective, Belgium, peer-reviewed, median age 73.0, 21 authors, study period 1 March, 2020 - 6 May, 2020.
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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