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Mortality-related risk factors of inpatients with diabetes and COVID-19: a multicenter retrospective study in Belgium

Servais et al., Annals of Endocrinology, doi:10.1016/j.ando.2023.08.002

Dec 2022

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Metformin for COVID-19

3rd treatment shown to reduce risk in July 2020

^*, now known with p < 0.00000000001 from 87 studies.

Lower risk for mortality, ventilation, ICU admission, hospitalization, progression, and recovery.

No treatment is 100% effective. Protocols combine complementary and synergistic treatments. ^* >10% efficacy in meta analysis with ≥3 clinical studies.

4,000+ studies for 60+ treatments. c19early.org

Retrospective 375 hospitalized diabetes patients in Belgium, showing lower risk of COVID-19 mortality with metformin use.

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risk of death, 49.0% lower, HR 0.51, p = 0.002, adjusted per study, multivariable.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates

Servais et al., 7 Dec 2022, retrospective, Belgium, peer-reviewed, median age 73.0, 21 authors, study period 1 March, 2020 - 6 May, 2020.

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