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All Studies   Meta Analysis    Recent:   

Gargling with povidone iodine has a short-term inhibitory effect on SARS-Cov-2 in COVID-19 patients

Seikai et al., Journal of Hospital Infection, doi:10.1016/j.jhin.2022.01.001
Jan 2022  
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PVP-I for COVID-19
13th treatment shown to reduce risk in February 2021
 
*, now with p = 0.000000004 from 21 studies.
Lower risk for mortality, cases, and viral clearance.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,400+ studies for 79 treatments. c19early.org
Small study of 11 patients showing a rapid short-term decrease of viral load in saliva samples with povidone-iodine.
Seikai et al., 15 Jan 2022, peer-reviewed, 9 authors.
This PaperPovidone-Iod..All
Gargling with povidone iodine has a short-term inhibitory effect on SARS-CoV-2 in patients with COVID-19
Tetsuya Seikai, Ayato Takada, Akira Hasebe, Masahiro Kajihara, Kosuke Okuya, T Sekiguchi (yamada), Wataru Kakuguchi, Satoshi Konno, Y Ohiro
Journal of Hospital Infection, doi:10.1016/j.jhin.2022.01.001
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Conflicts of Interest None declared.
References
Anderson, Sivalingam, Kang, Ananthanarayanan, Arumugam et al., Povidone-iodine demonstrates rapid in vitro virucidal activity against SARS-CoV-2, the virus causing COVID-19 disease, Infect Dis Ther
Bidra, Pelletier, Westover, Frank, Brown et al., Rapid In-Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Sasaki, Uemura, Sato, Toba, Sanaki et al., SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells, PLoS Pathog
Shet, Hong, Igo, Cataldo, Bhaskar, In Vitro Evaluation of the Virucidal Activity of Different Povidone-Iodine Formulations Against Murine and Human Coronaviruses, Infect Dis Ther
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Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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