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Gargling with povidone iodine has a short-term inhibitory effect on SARS-Cov-2 in COVID-19 patients

Seikai et al., Journal of Hospital Infection, doi:10.1016/j.jhin.2022.01.001
Jan 2022  
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Small study of 11 patients showing a rapid short-term decrease of viral load in saliva samples with povidone-iodine.
Seikai et al., 15 Jan 2022, peer-reviewed, 9 authors.
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This PaperPovidone-Iod..All
Gargling with povidone iodine has a short-term inhibitory effect on SARS-CoV-2 in patients with COVID-19
Tetsuya Seikai, Ayato Takada, Akira Hasebe, Masahiro Kajihara, Kosuke Okuya, T Sekiguchi (yamada), Wataru Kakuguchi, Satoshi Konno, Y Ohiro
Journal of Hospital Infection, doi:10.1016/j.jhin.2022.01.001
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Conflicts of Interest None declared.
References
Anderson, Sivalingam, Kang, Ananthanarayanan, Arumugam et al., Povidone-iodine demonstrates rapid in vitro virucidal activity against SARS-CoV-2, the virus causing COVID-19 disease, Infect Dis Ther
Bidra, Pelletier, Westover, Frank, Brown et al., Rapid In-Vitro Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Sasaki, Uemura, Sato, Toba, Sanaki et al., SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells, PLoS Pathog
Shet, Hong, Igo, Cataldo, Bhaskar, In Vitro Evaluation of the Virucidal Activity of Different Povidone-Iodine Formulations Against Murine and Human Coronaviruses, Infect Dis Ther
Late treatment
is less effective
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