Retrospective 42 PCR+ patients in Indonesia, showing significantly higher risk of symptomatic cases with vitamin D deficiency.
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risk of symptomatic case, 88.0% lower, RR 0.12, p < 0.001, high D levels 3 of 25 (12.0%), low D levels 17 of 17 (100.0%), NNT 1.1, >20ng/ml.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Savitri et al., 8 May 2021, retrospective, Indonesia, peer-reviewed, 5 authors.
Comparison between Vitamn D Level of Asymptomatic Confirmed Covid-19 Patients with Symptomatic Confirmed Covid-19 Patients in Makassar
Eka Savitri, Indra Irawan, Nova A L Pieter, Abdul Qadar Punagi, Nani Djufri
Vitamin D shows an important role in immune function. However,there is still little analysis regarding the role of vitamin D inpreventing infection and death fromCOVID-19.This researchaimed todetermine vitamin D levels inpatients with confirmed COVID-19. A crosssectional study was conducted. Researcher collected blood fromthemedian cubital vein of COVID-19 patients and examined the vitamin D levels in patients using the ELISA method.This research showed a comparison of serum vitaminD based on clinical manifestations of COVID-19 patients in all subjects. In20 patients with symptomatic COVID-19 clinical manifestations there were 17 patients (85 %) with vitamin Ddeficiency, 3 patients (15 %) with vitamin D insufficiency; To the contrary, there were noasymptomatic COVID-19 patientswith vitamin D deficiency, 18 patients with vitamin D insufficiency, and 4 patients with normal vitamin D levels.There was a significant relationship between the clinicalmanifestations of patients with COVID-19 and the patient's serum vitamin D levels where asymptomatic patientshad higher levels than that of symptomatic patients (p-value with the Chi-square test was 0.000 with p <0.001).In addition, there was a significant difference between vitamin D levels in asymptomatic and symptomatic patients whereserum vitamin D levels were obtained to be higher in the asymptomatic patient group than in thesymptomaticgroup.
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doi:10.2139/ssrn.3571484Carpagno, Vitamin D defciency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19, Journal of Endocrinological Investigation
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doi:10.1016/j.redox.2019.101295Ebadi, Montana, Perspective: improving vitamin D status in the management of COVID-19, Eur J ClinNutr
Horani, Nationality, Gender, Age, and Body Mass Index Influences on Vitamin D Concentration among Elderly Patients and Young Iraqi and Jordanian in Jordan, Biochemistry Research International
