Conv. Plasma
Nigella Sativa

All probiotics studies
Meta analysis
study COVID-19 treatment researchProbioticsProbiotics (more..)
Melatonin Meta
Metformin Meta
Azvudine Meta
Bromhexine Meta Molnupiravir Meta
Budesonide Meta
Colchicine Meta
Conv. Plasma Meta Nigella Sativa Meta
Curcumin Meta Nitazoxanide Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis    Recent:   

Efficiency of application of sorbed probiotics in complex therapy of pneumonia caused by SARS-CoV-2

Meskina et al., Therapeutic Archive, doi:10.26442/00403660.2021.04.200835
Jun 2021  
  Source   PDF   All Studies   Meta AnalysisMeta
Probiotics for COVID-19
18th treatment shown to reduce risk in March 2021
*, now known with p = 0.0000013 from 26 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,800+ studies for 60+ treatments.
RCT 100 pneumonia patients in Russia, showing faster symptom resolution with probiotic treatment (B. bifidum 1).
The immune effects of probiotics are strain-specific.
Meskina et al., 1 Jun 2021, Randomized Controlled Trial, Russia, peer-reviewed, 5 authors.
This PaperProbioticsAll
Efficiency of application of sorbed probiotics in complex therapy of pneumonia caused by SARS-CoV-2. Part 1. Heating clinical displays period
Elena R Meskina, Elena E Tselipanova, Marima K Khadisova, Lidiya A Galkina, Tatyana V Stashko
Terapevticheskii arkhiv, doi:10.26442/00403660.2021.04.200835
Аннотация Цель. Определить клиническую эффективность и безопасность сорбированных пробиотиков Bifidobacterium bifidum 1 (5×10 8 КОЕ) и B. bifidum 1 (5×10 7 КОЕ) в сочетании с Lactobacillus plantarum 8P-А3 (5×10 7 КОЕ) для лечения пневмонии, вызванной SARS-CoV-2, увзрослыхпациентов,неимеющихтяжелыхфакторовриска. Материалы и методы.Воткрытоерандомизированноепроспективноеисследованиевключены100пациентовстарше18летсплощадью поражениялегкихнакомпьютернойтомограмменеболее75%.РНКSARS-CoV-2вмазкахизносаиротоглоткиобнаружена(методомполимеразнойцепнойреакцииобратнойтранскрипции)у72%участников.ДиагностикаCOVID-19,стандартноеобследованиеилечение проведенысогласноВременнымметодическимрекомендациямМинздраваРоссии,версия8от03.09.2020.Впубликациипредставлены результатыпримененияB. bifidum1по3капсулы2разавденьвтечение10дней.
Ahlawat, Sharma, Immunological co-ordination between gut and lungs in SARS-CoV-2 infection, Virus Res, doi:10.1016/j.virusres.2020.198103
Artese, Svicher, Costa, Current status of antivirals and druggable targets of SARSCoV-2 and other human pathogenic coronaviruses, Drug Resist Updat, doi:10.1016/j.drup.2020.100721
Gautret, Million, Jarrot, Natural history of COVID-19 and therapeutic options, Expert Rev Clin Immunol, doi:10.1080/1744666X.2021.1847640
Geva-Zatorsky, Sefik, Kua, Mining the Human Gut Microbiota for Immunomodulatory Organisms, Cell, doi:10.1016/j.cell.2017.01.022
Giacomelli, Pezzati, Conti, Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study, Clin Infect Dis, doi:10.1093/cid/ciaa330
Gohil, Samson, Dastager, Dharne, Probiotics in the prophylaxis of COVID-19: something is better than nothing, Biotech, doi:10.1007/s13205-020-02554-1
Gou, Fu, Yue, Gut microbiota may underlie the predisposition of healthy individuals to COVID-19, MedRix, doi:10.1101/2020.04.22.20076091
Hani, Trieu, Saab, COVID-19 pneumonia: A review of typical CT findings and differential diagnosis, Diagn Interv Imaging, doi:10.1016/j.diii.2020.03.014
Kavaz, Tahir, Bilek, Clinical significance of smell and taste dysfunction and other related factors in COVID-19, Eur Arch Otorhinolaryngol, doi:10.1007/s00405-020-06503-9
Larenas-Linnemann, Rodríguez-Pérez, Arias-Cruz, Enhancing innate immunity against virus in times of COVID-19: Trying to untangle facts from fictions, World Allergy Organ J, doi:10.1016/j.waojou.2020.100476
Mazidi, Rezaie, Ferns, Vatanparast, Impact of Probiotic Administration on Serum C-Reactive Protein Concentrations: Systematic Review and Meta-Analysis of Randomized Control Trials, Nutrients, doi:10.3390/nu9010020
Mcilroy, Mullish, Goldenberg, Intestinal microbiome transfer, a novel therapeutic strategy for COVID-19 induced hyperinflammation?: In reply to, 'COVID-19: Immunology and treatment options, Clin Immunol, doi:10.1016/j.clim.2020.108542
Miller, Paradis, Houck, Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale, Psychiatry Res, doi:10.1016/0165-1781(92)90005-n
Nouri-Vaskeh, Sharifi, Khalili, Dyspneic and nondyspneic (silent) hypoxemia in COVID-19: Possible neurological m e c h a n i s m . C l i n N e u ro l N e u, ro s u rg, doi:10.1016/j.clineuro.2020.106217
Pan, Ye, Sun, Time Course of Lung Changes at Chest CT during Recovery from Coronavirus Disease 2019 (COVID-19), Radiology, doi:10.1148/radiol.2020200370
Santos, Da Silva, Do, Silva, Onset and duration of symptoms of loss of smell/taste in patients with COVID-19: A systematic review, Am J Otolaryngol, doi:10.1016/j.amjoto.2020.102889
Segal, Mak, Mullish, The gut microbiome: an underrecognised contributor to the COVID-19 pandemic?, Therap Adv Gastroenterol, doi:10.1177/1756284820974914
Shahbazi, Yasavoli-Sharahi, Alsadi, Probiotics in Treatment of Viral Respiratory Infections and Neuroinflammatory Disorders, Molecules, doi:10.3390/molecules25214891
Siemieniuk, Bartoszko, Ge, Drug treatments for Covid-19: living systematic review and network meta-analysis, BMJ, doi:10.1136/bmj.m2980
Stasi, Fallani, Voller, Silvestri, Treatment for COVID-19: An overview, Eur J Pharmacol, doi:10.1016/j.ejphar.2020.173644
Terapevticheskii Arkhiv, None, ТЕРАПЕВТИЧЕСКИЙ АРХИВ
Tobin, Laghi, Jubran, Why COVID-19 Silent Hypoxemia Is Baffling to Physicians, Am J Respir Crit Care Med, doi:10.1164/rccm.202006-2157CP
Vaira, Lechien, Khalife, Psychophysical Evaluation of the Olfactory Function: European Multicenter Study on 774 COVID-19
Ware, Snow, Kosinski, Gandek, Sf-36 Health Survey: Manual and Interpretation Guide
Yeoh, Zuo, Lui, Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19, Gut, doi:10.1136/gutjnl-2020-323020
Zuo, Liu, Zhang, Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19, Gut, doi:10.1136/gutjnl-2020-322294
Воз, Лекарственная терапия при COVID-19
Федерации, Временные методические рекомендации: профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop