Treatment With 25-Hydroxyvitamin D3 (Calcifediol) Is Associated With a Reduction in the Blood Neutrophil-to-Lymphocyte Ratio Marker of Disease Severity in Hospitalized Patients With COVID-19: A Pilot Multicenter, Randomized, Placebo-Controlled, Double-Blinded Clinical Trial
Ph.D Zhila Maghbooli, M.D, Saeid Mohammad Ali Sahraian, Saeidreza Jamalimoghadamsiahkali, M.D Asma Asadi, Azadeh Zarei, M.D Abolfazl Zendehdel, M.D Tarlan Varzandi, M.S.c Sara Mohammadnabi, Neda Alijani, Mehrdad Mehrdad Karimi, M.D Arash Shirvani, Ph.D Michael F Holick
Endocrine Practice, doi:10.1016/j.eprac.2021.09.016
Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. Treatment with 25-hydroxyvitamin D3 (calcifediol) is associated with a reduction in the blood neutrophil-to-lymphocyte ratio marker of disease severity in patients hospitalized with COVID-19: a pilot, multicenter, randomized, placebo-controlled double blind clinical trial
J o u r n a l P r e -p r o o f
J o u r n a l P r e -p r o o f
Declaration of interests ☐ The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. ☒The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: The authors declare the following personal relationships which may be considered as potential competing interests: Michael F. Holick was a consultant for Quest Diagnostics Inc. is a consultant for Ontometrics Inc and Biogena Inc., received a grant from Carbogen Amcis BV and was on the speaker's Bureau for Abbott Inc. The remaining authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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