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0 0.5 1 1.5 2+ Severe case 55% Improvement Relative Risk c19early.org/d Macaya et al. Vitamin D for COVID-19 Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 80 patients in Spain Lower severe cases with higher vitamin D levels (not stat. sig., p=0.07) Macaya et al., Nutr. Hosp., doi:10.20960/nh.03193 Favors vitamin D Favors control

Interaction between age and vitamin D deficiency in severe COVID-19 infection

Macaya et al., Nutr. Hosp., doi:10.20960/nh.03193
Macaya et al., Interaction between age and vitamin D deficiency in severe COVID-19 infection, Nutr. Hosp., doi:10.20960/nh.03193
Oct 2020   Source   PDF  
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Retrospective 80 hospitalized patients in Spain showing higher risk of severe COVID-19 with vitamin D deficiency.
This is the 21st of 175 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 18 vigintillion).
risk of severe case, 55.0% lower, RR 0.45, p = 0.07, high D levels 11 of 35 (31.4%), low D levels 20 of 45 (44.4%), NNT 7.7, inverted to make RR<1 favor high D levels, odds ratio converted to relative risk, >20ng/mL.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Macaya et al., 21 Oct 2020, retrospective, Spain, peer-reviewed, 8 authors.
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