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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ ICU admission 45% Improvement Relative Risk Vitamin D for COVID-19  Lau et al.  Sufficiency Are vitamin D levels associated with COVID-19 outcomes? Retrospective 20 patients in the USA Lower ICU admission with higher vitamin D levels (not stat. sig., p=0.29) c19early.org Lau et al., medRxiv, April 2020 Favors vitamin D Favors control

Vitamin D Insufficiency is Prevalent in Severe COVID-19

Lau et al., medRxiv, doi:10.1101/2020.04.24.20075838
Apr 2020  
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Vitamin D for COVID-19
8th treatment shown to reduce risk in October 2020
 
*, now known with p < 0.00000000001 from 119 studies, recognized in 7 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,800+ studies for 60+ treatments. c19early.org
Analysis of 20 hospitalized COVID-19 patients, 13 requiring ICU admission. 84.6% of the ICU patients had low vitamin D levels versus 57.1% of the non-ICU patients.
This is the 1st of 192 COVID-19 sufficiency studies for vitamin D, which collectively show higher levels reduce risk with p<0.0000000001 (1 in 611 vigintillion).
risk of ICU admission, 45.0% lower, RR 0.55, p = 0.29, high D levels 2 of 5 (40.0%), low D levels 11 of 15 (73.3%), NNT 3.0, >30ng/mL.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Lau et al., 28 Apr 2020, retrospective, USA, preprint, 7 authors.
This PaperVitamin DAll
Abstract: medRxiv preprint doi: https://doi.org/10.1101/2020.04.24.20075838; this version posted April 28, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission. Vitamin D insufficiency is prevalent in severe COVID-19 Frank H. Lau, MD, FACS1, Rinku Majumder, PhD2, Radbeh Torabi, MD1, Fouad Saeg, BS3, Ryan Hoffman, BS4, Jeffrey D. Cirillo, PhD5, Patrick Greiffenstein, MD, FACS1 Affiliations: 1. Department of Surgery, Louisiana State University Health Sciences Center New Orleans (LSUHSC-NO) 2. Department of Biochemistry, LSUHSC-NO 3. Tulane School of Medicine 4. LSUHSC-NO School of Medicine 5. Department of Microbial Pathogenesis and Immunology, Texas A&M College of Medicine Corresponding Author: Dr. Frank H. Lau, MD, FACS; Department of Surgery, Louisiana State University Health Sciences Center New Orleans, 1542 Tulane Ave, 7th Floor, New Orleans, LA 70112; email: flau@lsuhsc.edu; phone: (504) 412-1240 NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice. medRxiv preprint doi: https://doi.org/10.1101/2020.04.24.20075838; this version posted April 28, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
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