Tolerability and usability of 0.5% PVP-I gargles and nasal drops in 6692 patients: Observational study
Sapna Mubarak Muhamed Khan, Sapna Ramkrishna Parab
American Journal of Otolaryngology, doi:10.1016/j.amjoto.2020.102880
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References
Ader, Paul, Reinhardt, Effect of mouth rinsing with two polyvinylpyrrolidone-iodine mixtures on iodine absorption and thyroid function, J Clin Endocrinol Metab
Domingo, Farrales, Loya, Pura, Uy, The effect of 1% povidone iodine as a pre-procedural mouthrinse in 20 patients with varying degrees of oral hygiene, J Philipp Dent Assoc
Eggers, Eickmann, Zorn, Rapid and effective Virucidal activity of povidoneiodine products against Middle East respiratory syndrome coronavirus (MERS-CoV) and modified Vaccinia virus Ankara (MVA), Infect Dis Ther,
doi:10.1007/s40121-015-0091-9Eggers, Infectious disease management and control with povidone iodine, Infect Dis Ther
Eggers, Koburger-Janssen, Eickmann, Zorn, In vitro bactericidal and virucidal efficacy of povidone-iodine gargle/mouthwash against respiratory and oral tract pathogens, Infect Dis Ther,
doi:10.1007/s40121-018-0200-7Khan, Parab, 0.5% povidone iodine irrigation in otorhinolaryngology surgical practice during COVID 19 pandemic, Am J Otolaryngol,
doi:10.1016/j.amjoto.2020.102687Khan, Parab, Paranjape, Repurposing 0.5% povidone iodine solution in otorhinolaryngology practice in covid 19 pandemic, Am J Otolaryngol,
doi:10.1016/j.amjoto.2020.102618Lachapelle, Castel, Casado, Antiseptics in the era of bacterial resistance: a focus on povidone iodine, Future Med
Madan, Sequeira, Shenoy, Shetty, The effect of three mouthwashes on radiation-induced oral mucositis in patients with head and neck malignancies: a randomized control trial, J Cancer Res Ther
Mullings, Panchmatia, Samoy, Topical povidone-iodine as an adjunctive treatment for recalcitrant chronic rhinosinusitis, European Journal of Rhinology and Allergy,
doi:10.5152/ejra.2019.166Nagatake, Ahmed, Oishi, Prevention of respiratory infections by povidoneiodine gargle, Dermatology
Panchmatia, Payandeh, Al-Salman, The efficacy of diluted topical povidone-iodine rinses in the management of recalcitrant chronic rhinosinusitis: a prospective cohort study, Eur Arch Otorhinolaryngol Published Online First,
doi:10.1007/s00405-019-05628-wRackur, New aspects of mechanism of action of povidoneiodine, J Hosp Infect
Rahn, Adamietz, Boettcher, Schaefer, Reimer et al., Povidoneiodine to prevent mucositis in patients during antineoplastic radiochemotherapy, Dermatology
Reimer, Wichelhaus, Schafer, Antimicrobial effectiveness of povidoneiodine and consequences for new application areas, Dermatology
Rezapoor, Nicholson, Tabatabaee, Chen, Maltenfort et al., Povidone-iodine-based solutions for decolonization of nasal Staphylococcus aureus: a randomized, prospective, placebo-controlled study, J Arthroplasty,
doi:10.1016/j.arth.2017.04.039Sungnak, Huang, 'ecavin, SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes, Nat Med
Wewalka, Stary, Bosse, Duerr, Reimer, Efficacy of povidone-iodine vaginal suppositories in the treatment of bacterial vaginosis, Dermatology
Zou, Ruan, Huang, SARS-CoV-2 viral load in upper respiratory specimens of infected patients, N Engl J Med
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