Association of vitamin D and severity of COVID-19 in children
Pegah Karimian, Motahareh Sadat Tahami, Shirin Sayyahfar, Motahare Aghajani Delavar
European Journal of Translational Myology, doi:10.4081/ejtm.2022.10453
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'abstract': '<jats:p>Vitamin has a major role in the functions of the immune system, and the efficacy of '
'this vitamin in reducing inflammation has been identified. Considering the effects of vitamin '
'D, this study research was performed for investigating the relationship between vitamin D and '
'the severity of COVID-19 in children. This cross-sectional study was performed on 101 '
'children infected with the new coronavirus from September 2020 to October 2021. Information '
'on vitamin D levels, demographic factors, and clinical and laboratory findings were '
'documented in information forms and prepared for statistical analyses. The average of '
'children was 2.85 ± 0.85 years. Low oxygen saturation was observed in 35.3% of infected '
'children. The level of involvement was higher in subjects with vitamin D levels higher than '
'30 and less than 10 ng/ml (p = 0.04). Clinical signs in cases with deficient and sufficient '
'vitamin D levels were more severe in terms of tachypnea and tachycardia (p = 0.01). Children '
'with vitamin D lower than 10 ng/ml showed more frequency (p = 0.02). Cases with moderate '
'vitamin D had fewer gastrointestinal complications (p = 0.03). Also, oxygen levels were lower '
'in children who had low levels of vitamin D (p = 0.02). Vitamin D levels were associated with '
'levels of involvement, tachycardia, tachypnea, clinical signs, gastrointestinal problems, and '
'O2 levels. Moderate vitamin D levels in children are a critical issue that should be '
'considered.</jats:p>',
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