Metformin for COVID-19
3rd treatment shown to reduce risk in
July 2020
No treatment is 100% effective. Protocols
combine treatments. * >10%
efficacy, ≥3 studies.
4,800+ studies for
95 treatments. c19early.org
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death or long COVID, 11.3% lower, HR 0.89, p = 0.11, treatment 42,275, control 6,713, combined.
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death or long COVID, 21.0% lower, HR 0.79, p < 0.001, treatment 42,275, control 6,713, N3C, EHR code.
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death or long COVID, 15.0% lower, HR 0.85, p < 0.001, treatment 42,275, control 6,713, N3C, phenotype.
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death or long COVID, 13.0% lower, HR 0.87, p = 0.32, treatment 30,748, control 5,933, PCORnet, EHR code.
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death or long COVID, 4.0% higher, HR 1.04, p = 0.26, treatment 30,748, control 5,933, PCORnet, phenotype.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |