Analgesics
Antiandrogens
Antihistamines
Azvudine
Bromhexine
Budesonide
Colchicine
Conv. Plasma
Curcumin
Famotidine
Favipiravir
Fluvoxamine
Hydroxychlor..
Ivermectin
Lifestyle
Melatonin
Metformin
Minerals
Molnupiravir
Monoclonals
Naso/orophar..
Nigella Sativa
Nitazoxanide
PPIs
Paxlovid
Quercetin
Remdesivir
Thermotherapy
Vitamins
More

Other
Feedback
Home
 
next
study
previous
study
c19early.org COVID-19 treatment researchMetforminMetformin (more..)
Melatonin Meta
Metformin Meta
Antihistamines Meta
Azvudine Meta Molnupiravir Meta
Bromhexine Meta
Budesonide Meta
Colchicine Meta Nigella Sativa Meta
Conv. Plasma Meta Nitazoxanide Meta
Curcumin Meta PPIs Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis       

The Proportion and Associated Factors for Mortality among COVID-19 Infection with Diabetes in Iraq

Hussein et al., The Review of Diabetic Studies, doi:10.1900/RDS.2024.20.12
Jun 2024  
  Post
  Facebook
Share
  Source   PDF   All Studies   Meta AnalysisMeta
Mortality 64% Improvement Relative Risk Metformin for COVID-19  Hussein et al.  Prophylaxis Is prophylaxis with metformin beneficial for COVID-19? Retrospective 545 patients in Iraq Study compares with insulin, results vs. placebo may differ Lower mortality with metformin (p=0.048) c19early.org Hussein et al., The Review of Diabetic.., Jun 2024 Favorsmetformin Favorsinsulin 0 0.5 1 1.5 2+
Metformin for COVID-19
3rd treatment shown to reduce risk in July 2020, now with p < 0.00000000001 from 99 studies.
No treatment is 100% effective. Protocols combine treatments.
5,100+ studies for 112 treatments. c19early.org
Retrospective 545 hospitalized COVID-19 patients with diabetes showing high mortality (33%). Metformin, SGLT inhibitors, and DPP4 inhibitors were associated with lower mortality compared with insulin.
risk of death, 63.8% lower, RR 0.36, p = 0.048, treatment 30 of 158 (19.0%), control 60 of 110 (54.5%), NNT 2.8, adjusted per study, odds ratio converted to relative risk, multivariable.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hussein et al., 30 Jun 2024, retrospective, Iraq, peer-reviewed, 4 authors, this trial compares with another treatment - results may be better when compared to placebo.
This PaperMetforminAll
The Proportion and Associated Factors for Mortality among COVID-19 Infection with Diabetes in Iraq
Hafed Ibrahem Hussein, Azidah Abdul Kadir, Nani Draman, Wan Mohd Izani, Wan Mohamed
doi:10.1900/RDS.2024.20.12
Objective: The study aims to determine the proportion, clinical characteristics, and associated factors for the mortality among hospitalised COVID-19 patients with diabetes in Ramadi, Iraq. Methods: This retrospective cohort study included all adult diabetic patients with laboratory-confirmed COVID-19 who were hospitalised between January 2020 and December 2020 in Ramadi Province, Iraq. Data on demographics, medical history, and laboratory investigations were obtained from medical records. The poor outcomes were mortality during hospitalisation. Multivariate logistic regression was used to analyse for the associated factors for mortality. Results: A total of 545 health records of diabetic patients were reviewed. There were 340 males (62.4%) and 205 females (37.6%). The mean age was 64.54±10.86 years. The proportion of mortality was 32.84%. The protective factors for mortality were rural residency, duration of hospitalisation, and diabetic medication (SGLT inhibitors, DPP4 inhibitors and metformin). Cardiac disease, liver disease, temperature, CRP and D-dimer level were found to be predictive factors for mortality. Conclusion: The study revealed that the proportion of mortality among diabetic patients with COVID-19 infection was high in Iraq. The findings highlighted the predictive and protective factors among this vulnerable group for poor outcomes.
Rev Diabet Stud (2024) 20: [12] [13] [14] [15] [16] Copyright © by Lab & Life Press of statistics at the Ramadi Teaching Hospital, Anbar Province, Iraq, for their cooperation during data collection. Conflict of Interest The authors declare that there is no conflict of interest
References
Cariou, Hadjadj, Wargny, Pichelin, Al-Salameh et al., Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study, Diabetologia
Chen, Yang, Cheng, Chen, Peng et al., Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication, Diabetes Care
Ciotti, Ciccozzi, Terrinoni, Jiang, Wang et al., The COVID-19 pandemic, Crit Rev Clin Lab Sci
Cuadros, Branscum, Mukandavire, Miller, Mackinnon, Dynamics of the COVID-19 epidemic in urban and rural areas in the United States, Ann Epidemiol
Fadini, Morieri, Longato, Avogaro, Prevalence and impact of diabetes among people infected with SARS-CoV-2, J Endocrinol Invest
Huang, Lim, Pranata, Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression, Diabetes Metab Syndr
Izzi-Engbeaya, Distaso, Amin, Yang, Idowu et al., Adverse outcomes in COVID-19 and diabetes: a retrospective cohort study from three London teaching hospitals, BMJ Open Diabetes Res Care
Miller, Bhattacharyya, Miller, Diabetes mellitus increases the risk of hospital mortality in patients with Covid-19: Systematic review with metaanalysis, Medicine
Mirsoleymani, Taherifard, Taherifard, Taghrir, Marzaleh et al., Predictors of mortality among covid-19 patients with or without comorbid diabetes mellitus, Acta Medica Iranica
Mishra, Pathak, Mohakuda, Tilak, Sen, Relation of D-dimer levels of COVID-19 patients with diabetes mellitus, Diabetes Metab Syndr
Ong, Tan, Cañete, Lim, Robles, Association Between Metformin Use and Mortality among Patients with Type 2 Diabetes Mellitus Hospitalized for COVID-19 Infection, J ASEAN Fed Endocr Soc
Patoulias, Doumas, Dipeptidyl Peptidase-4 Inhibitors and COVID-19-Related Deaths among Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Observational Studies, Endocrinol Metab
Porcheddu, Serra, Kelvin, Rubino, Similarity in Case Fatality Rates (CFR) of COVID-19/SARS-COV-2 in Italy and China, J Infect Dev Ctries
Ramirez, Lee, COVID-19 Emergence and Social and Health Determinants in Colorado: A Rapid Spatial Analysis, Int J Environ Res Public Health
Saha, Al-Rifai, Saha, Diabetes prevalence and mortality in COVID-19 patients: a systematic review, meta-analysis, and meta-regression, J Diabetes Metab Disord
Yang, Zhong, Tian, Xie, Fu et al., The effect of diabetes on mortality of COVID-19: A protocol for systematic review and meta-analysis, Medicine
Zhang, Schwartz, Spatial Disparities in Coronavirus Incidence and Mortality in the United States: An Ecological Analysis as of May 2020, J Rural Health
Loading..
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop   
Submit